Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | CPS1 | P31327 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12636054 | 0.85 | ELANE (0.50) | MAOBMAOACES2CES1SOS1 | |
| SCHEMBL31621879 | 0.84 | LMNA (0.52) | MAOBMAOACYP4F2CYP4A11GAA | |
| SCHEMBL823757 | 0.84 | LMNA (0.52) | MAOBMAOACYP4F2CYP4A11GAA | |
| SCHEMBL17355655 | 0.81 | CDK8 (0.41) | MAPT | |
| SCHEMBL18697358 | 0.79 | CES2 (0.46) | MAOBMAOACES2CES1SOS1 | |
| SCHEMBL12636049 | 0.79 | CES2 (0.39) | MAOBMAOACES2CES1SOS1 | |
| SCHEMBL18272392 | 0.78 | CES2 (0.45) | MAOBMAOACES2CES1SOS1 | |
| SCHEMBL3871529 | 0.78 | LMNA (0.43) | MAOBMAOACES2CES1RAB9A | |
| SCHEMBL12636024 | 0.78 | ELANE (0.40) | MAOBMAOACES2CES1SOS1 | |
| SCHEMBL4805336 | 0.76 | CES2 (0.43) | MAOBMAOACES2CES1SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206460-B1 | L-PHENYLALANINE DEHYDROGENASE AND USE THEREOF | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1993-08-11 | — | — | EP | disclosed |
| EP-0513872-A1 | L-phenylalanine dehydrogenase and use thereof | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-11-19 | — | — | EP | disclosed |
| US-4849345-A | L-phenylalanine dehydrogenase and use thereof | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1989-07-18 | — | — | US | disclosed |
| EP-0206460-A2 | L-phenylalanine dehydrogenase and use thereof | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-12-30 | — | — | EP | disclosed |