SCHEMBL9508351

SCHEMBL9508351

Cc1cnc(-c2cccc3ccccc23)s1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.49
KDM4E B2RXH2 2/20 0.49
HPGD P15428 2/20 0.49
LMNA P02545 1/20 0.49
HSD17B10 Q99714 1/20 0.49
HTR2C P28335 9/20 0.47
ALOX15 P16050 1/20 0.44
DCTPP1 Q9H773 1/20 0.44
ENPP3 O14638 1/20 0.42
ENPP1 P22413 1/20 0.42
TGFBR1 P36897 1/20 0.41
DHFR P00374 1/20 0.41
PTPN11 Q06124 1/20 0.40
CYP2A6 P11509 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4585665 0.81 HTR2C (0.48) ALDH1A1KDM4EHPGDLMNAHSD17B10
SCHEMBL4600855 0.79 HTR2C (0.47) ALDH1A1KDM4EHPGDLMNAHSD17B10
SCHEMBL11095741 0.79 HTR2C (0.50) ALDH1A1KDM4EHPGDLMNAHSD17B10
SCHEMBL1538345 0.79 HTR2C (0.44) ALDH1A1KDM4EHPGDLMNAHSD17B10
SCHEMBL25764678 0.79 HTR2C (0.44) ALDH1A1KDM4EHPGDLMNAHSD17B10
SCHEMBL10988411 0.79 HTR2C (0.47) ALDH1A1KDM4EHPGDLMNAHSD17B10
SCHEMBL23176768 0.78 ALDH1A1 (0.41) ALDH1A1KDM4EHPGDLMNADCTPP1
SCHEMBL12914319 0.78 HTR2C (0.46) ALDH1A1KDM4EHPGDLMNAHSD17B10
SCHEMBL28745186 0.78 PTPN1 (0.50) ALDH1A1KDM4EHPGDLMNAHSD17B10
SCHEMBL30987375 0.78 PTPN1 (0.50) ALDH1A1KDM4EHPGDLMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0297804-B1 SILVER HALIDE PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1993-08-18 EP disclosed
US-4863846-A SULFUR KONICA CORPORATION (JP) 1989-09-05 US disclosed
EP-0297804-A2 Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1989-01-04 EP disclosed