Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11060360 | 0.87 | LTA4H (0.61) | ACEACE2LTA4HTSHR | |
| SCHEMBL5710967 | 0.86 | ACE (0.61) | ACEOPRM1ACE2LTA4HTSHR | |
| Oxalic Acid SCHEMBL11058316 | 0.85 | ACE (0.50) | ACEOPRM1ACE2XIAP | |
| SCHEMBL30165330 | 0.84 | ACE (0.57) | ACEACE2LTA4HTSHR | |
| SCHEMBL5030497 | 0.80 | ACE (0.54) | ACEOPRM1ACE2LTA4HTSHR | |
| SCHEMBL5030487 | 0.80 | ACE (0.54) | ACEOPRM1ACE2LTA4HTSHR | |
| SCHEMBL9508348 | 0.80 | ACE (0.59) | ACEOPRM1ACE2 | |
| SCHEMBL30358542 | 0.79 | ACE (0.58) | ACEOPRM1ACE2LTA4HTSHR | |
| SCHEMBL29630391 | 0.79 | ACE (0.55) | ACEOPRM1ACE2LTA4HTSHR | |
| SCHEMBL18064472 | 0.79 | ACE (0.53) | ACEOPRM1ACE2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316218-B1 | L-PROLINE DERIVATIVES, THEIR PREPARATION AND BIOLOGICAL APPLICATIONS THEREOF | EKITA Investments N.V. (NA) | 1993-09-15 | — | — | EP | claimed |