Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MYOC | Q99972 | 1/20 | 0.40 |
| ▸ | DDX3X | O00571 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10362498 | 0.89 | SMN1; SMN2 (0.47) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL9510528 | 0.87 | MAPT (0.43) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL10362972 | 0.81 | MAPK1 (0.42) | ALDH1A1MEN1KMT2ALMNANPSR1 | |
| SCHEMBL10364361 | 0.80 | TSHR (0.45) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL27484194 | 0.79 | MEN1 (0.50) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL9509361 | 0.79 | MAPK1 (0.42) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL10364446 | 0.79 | SMN1; SMN2 (0.46) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL9508005 | 0.79 | SMN1; SMN2 (0.54) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL4014462 | 0.78 | ALDH1A1 (0.64) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL10362546 | 0.77 | MAPT (0.40) | ALDH1A1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317645-B1 | 4H-3,1-BENZOXAZIN-4-ONE COMPOUNDS AND SERINE PROTEASE-INHIBITING MEDICINAL COMPOSITION CONTAINING SAME | TEIJIN LIMITED (JP) | 1993-09-15 | — | — | EP | disclosed |
| EP-0466944-A1 | 4H-3,1-BENZOXAZIN-4-ONE COMPOUND AND ELASTASE INHIBITOR COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| US-4980287-A | ANTIINFLAMMATORY AGENTS; INHIBITOR OF DEGENERATION AND DESTRUCTION OF TISSUES | TEIJIN LIMITED (JP) | 1990-12-25 | — | — | US | disclosed |
| EP-0317645-A1 | 4H-3,1-BENZOXAZIN-4-ONE COMPOUNDS AND SERINE PROTEASE-INHIBITING MEDICINAL COMPOSITION CONTAINING SAME | TEIJIN LIMITED (JP) | 1989-05-31 | — | — | EP | disclosed |