Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509533 | 0.89 | SMN1; SMN2 (0.48) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL9788334 | 0.89 | MEN1 (0.53) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL14679449 | 0.76 | KMT2A (0.57) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL14679398 | 0.74 | CA1 (0.64) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL14617667 | 0.74 | SMN1; SMN2 (0.81) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL11731507 | 0.72 | KMT2A (0.65) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL2730689 | 0.71 | SMN1; SMN2 (0.85) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL13932527 | 0.70 | KMT2A (0.83) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL9508408 | 0.70 | HPGD (0.61) | KMT2AMEN1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL660986 | 0.70 | KMT2A (0.62) | KMT2AMEN1NPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3017051-A | — | — | None | — | — | JP | disclosed |
| EP-0398059-B1 | CYCLOPROPANOYLAMINOACID AMIDE DERIVATIVES | BAYER AG (DE) | 1993-08-25 | — | — | EP | disclosed |
| US-5034408-A | Fungicides of dihalocyclopropanoylamino acid amides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-23 | — | — | US | disclosed |
| JP-H0317051-A | CYCLOPROPANOYLAMINO ACID AMIDE DERIVATIVE | BAYER AG | 1991-01-25 | — | — | JP | disclosed |
| EP-0398059-A1 | Cyclopropanoylaminoacid amide derivatives | BAYER AG (DE) | 1990-11-22 | — | — | EP | disclosed |