Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171709 | 0.87 | KMT2A (0.66) | KMT2AMEN1ALDH1A1NPC1LMNA | |
| SCHEMBL7529131 | 0.84 | GAA (0.59) | KMT2AMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL14679398 | 0.84 | CA1 (0.64) | KMT2AMEN1ALDH1A1NPC1LMNA | |
| SCHEMBL12840799 | 0.83 | ALDH1A1 (0.51) | KMT2AALDH1A1RAB9ACA1CA2 | |
| SCHEMBL25567577 | 0.81 | KMT2A (0.60) | KMT2AMEN1ALDH1A1NPC1LMNA | |
| SCHEMBL12839912 | 0.81 | TPSAB1 (0.52) | KMT2AALDH1A1NPC1RAB9ACA12 | |
| SCHEMBL14617667 | 0.80 | SMN1; SMN2 (0.81) | KMT2AMEN1ALDH1A1NPC1LMNA | |
| SCHEMBL14679426 | 0.80 | MMP13 (0.54) | ALDH1A1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL13932527 | 0.79 | KMT2A (0.83) | KMT2AMEN1ALDH1A1NPC1LMNA | |
| SCHEMBL660986 | 0.79 | KMT2A (0.62) | KMT2AMEN1ALDH1A1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367668-B2 | Pyridazinone derivatives | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 2013-02-05 | — | — | US | disclosed |