Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1136202 | 0.79 | HPGD (0.66) | HPGDSMN1; SMN2NPSR1GAAMEN1 | |
| SCHEMBL20415657 | 0.73 | MME (0.47) | HPGDSMN1; SMN2NPSR1MMECYP3A4 | |
| SCHEMBL28306633 | 0.72 | MME (0.50) | MMEKMT2ACYP3A4CYP2C19LMNA | |
| SCHEMBL12858044 | 0.72 | TSHR (0.68) | SMN1; SMN2GAAMMERAB9ALMNA | |
| SCHEMBL7102263 | 0.68 | ALDH1A1 (0.45) | NPSR1MMEMEN1KMT2ACYP3A4 | |
| SCHEMBL7102260 | 0.68 | ALDH1A1 (0.45) | NPSR1MMEMEN1KMT2ACYP3A4 | |
| SCHEMBL3000839 | 0.68 | MME (0.42) | MMEKMT2ALMNAALDH1A1TSHR | |
| SCHEMBL1651948 | 0.68 | MME (0.55) | SMN1; SMN2MMECYP3A4CYP2C19LMNA | |
| SCHEMBL21410865 | 0.68 | — | — | |
| SCHEMBL7693995 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398059-B1 | CYCLOPROPANOYLAMINOACID AMIDE DERIVATIVES | BAYER AG (DE) | 1993-08-25 | — | — | EP | disclosed |
| US-5034408-A | Fungicides of dihalocyclopropanoylamino acid amides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-23 | — | — | US | disclosed |
| EP-0398059-A1 | Cyclopropanoylaminoacid amide derivatives | BAYER AG (DE) | 1990-11-22 | — | — | EP | disclosed |