Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CTH | P32929 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | ECE1 | P42892 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | CPA1 | P15085 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15252887 | 0.93 | MME (0.38) | MMEEGLN1ALDH1A1TDP1LMNA | |
| SCHEMBL28306633 | 0.81 | MME (0.50) | MMEEGLN1ALDH1A1TDP1LMNA | |
| SCHEMBL13448190 | 0.79 | ALDH1A1 (0.36) | ALDH1A1LMNAKMT2A | |
| SCHEMBL1651948 | 0.76 | MME (0.55) | MMEEGLN1ALDH1A1TDP1LMNA | |
| SCHEMBL3009135 | 0.76 | POLB (0.41) | ALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL2998916 | 0.76 | CYP3A4 (0.37) | ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL3000934 | 0.72 | EPHX1 (0.47) | LMNA | |
| SCHEMBL2998922 | 0.72 | NSD2 (0.32) | NSD2FFAR3 | |
| SCHEMBL30987859 | 0.68 | MME (0.42) | MMEEGLN1ALDH1A1TDP1LMNA | |
| SCHEMBL4313621 | 0.68 | MME (0.39) | MMEALDH1A1TDP1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168567-B1 | Uses of dithiolane compounds for the photoprotection of the skin, dithiolane compounds and compositions containing same | ORÉAL L (FR) | 2015-12-16 | — | — | EP | claimed |
| US-8617524-B2 | Depigmenting keratin materials utilizing dithiolane compounds | L'OREAL (FR) | 2013-12-31 | — | — | US | claimed |
| US-8535647-B2 | Cosmetic/sunscreen compositions containing dibenzoylmethane compounds and dithiolane compound photostabilizers therefor | L'OREAL (FR) | 2013-09-17 | — | — | US | claimed |
| US-8530511-B2 | Administration of dithiolane compounds for photoprotecting the skin | L'OREAL (FR) | 2013-09-10 | — | — | US | claimed |
| EP-2174644-B1 | Cosmetic composition comprising a dibenzoylmethane derivative and a dithiolane; Photostabilization of a dibenzoylmethane derivative | OREAL (FR) | 2012-11-14 | — | — | EP | claimed |
| US-20100197759-A1 | Administration of dithiolane compounds for photoprotecting the skin | L'OREAL (FR) | 2010-08-05 | — | — | US | claimed |
| US-20100135942-A1 | Depigmenting keratin materials utilizing dithiolane compounds | L'OREAL (FR) | 2010-06-03 | — | — | US | claimed |
| US-20100086502-A1 | Cosmetic/sunscreen compositions containing dibenzoylmethane compounds and dithiolane compound photostabilizers therefor | L'OREAL (FR) | 2010-04-08 | — | — | US | claimed |
| EP-2168567-B1 | Uses of dithiolane compounds for the photoprotection of the skin, dithiolane compounds and compositions containing same | ORÉAL L (FR) | 2015-12-16 | — | — | EP | disclosed |
| US-8617524-B2 | Depigmenting keratin materials utilizing dithiolane compounds | L'OREAL (FR) | 2013-12-31 | — | — | US | disclosed |
| US-8535647-B2 | Cosmetic/sunscreen compositions containing dibenzoylmethane compounds and dithiolane compound photostabilizers therefor | L'OREAL (FR) | 2013-09-17 | — | — | US | disclosed |
| US-8535647-B2 | Cosmetic/sunscreen compositions containing dibenzoylmethane compounds and dithiolane compound photostabilizers therefor | L'OREAL (FR) | 2013-09-17 | — | — | US | disclosed |
| US-8535647-B2 | Cosmetic/sunscreen compositions containing dibenzoylmethane compounds and dithiolane compound photostabilizers therefor | L'OREAL (FR) | 2013-09-17 | — | — | US | disclosed |
| US-8530511-B2 | Administration of dithiolane compounds for photoprotecting the skin | L'OREAL (FR) | 2013-09-10 | — | — | US | disclosed |
| EP-2174644-A1 | Cosmetic composition comprising a dibenzoylmethane derivative and a dithiolane; Photostabilization of a dibenzoylmethane derivative | L'OREAL (FR) | 2010-04-14 | — | — | EP | disclosed |
| US-20100086502-A1 | Cosmetic/sunscreen compositions containing dibenzoylmethane compounds and dithiolane compound photostabilizers therefor | L'OREAL (FR) | 2010-04-08 | — | — | US | disclosed |
| US-20100086502-A1 | Cosmetic/sunscreen compositions containing dibenzoylmethane compounds and dithiolane compound photostabilizers therefor | L'OREAL (FR) | 2010-04-08 | — | — | US | disclosed |
| US-20100086502-A1 | Cosmetic/sunscreen compositions containing dibenzoylmethane compounds and dithiolane compound photostabilizers therefor | L'OREAL (FR) | 2010-04-08 | — | — | US | disclosed |
| EP-2168567-A1 | Uses of dithiolane compounds for the photoprotection of the skin, dithiolane compounds and compositions containing same | L'Oréal (FR) | 2010-03-31 | — | — | EP | disclosed |
| EP-2168567-A1 | Uses of dithiolane compounds for the photoprotection of the skin, dithiolane compounds and compositions containing same | L'Oréal (FR) | 2010-03-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100086502-A1 | Cosmetic/sunscreen compositions containing dibenzoylmethane compounds and dithiolane compound photostabilizers therefor | NOTUM, DDT, FDFT1 | MME 4626/4885EGLN1 1273/4885ALDH1A1 206/4885 |
| US-20100197759-A1 | Administration of dithiolane compounds for photoprotecting the skin | GPX1, GPX4, TXN | MME 3220/4885EGLN1 1631/4885ALDH1A1 270/4885 |
| US-20100135942-A1 | Depigmenting keratin materials utilizing dithiolane compounds | KRT18, NR1D1, RER1 | MME 4532/4885EGLN1 4613/4885ALDH1A1 994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.