Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31152467 | 0.74 | TRPM8 (0.48) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL1659675 | 0.74 | TRPM8 (0.48) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL28328623 | 0.73 | TRPM8 (0.55) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL4167467 | 0.72 | EPHX1 (0.39) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL28280924 | 0.72 | TRPM8 (0.46) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL4167469 | 0.71 | EPHX1 (0.38) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL31148535 | 0.71 | TRPM8 (0.52) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL21380099 | 0.70 | TRPM8 (0.47) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL4389935 | 0.69 | TRPM8 (0.65) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL13465301 | 0.69 | TRPM8 (0.65) | TRPM8TRPA1EPHX1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337613-B1 | DEVICE COMPRISING MEANS FOR PROTECTING AND DISPENSING FLUID SENSITIVE MEDICAMENT | ALZA CORPORATION (US) | 1993-07-28 | — | — | EP | claimed |
| EP-0337613-A1 | Device comprising means for protecting and dispensing fluid sensitive medicament | ALZA CORPORATION (US) | 1989-10-18 | — | — | EP | claimed |