Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.49 |
| ▸ | TK1 | P04183 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.41 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3490250 | 0.88 | KIF11 (0.49) | KIF11TK1KCNH2SLC6A1SLC6A11 | |
| SCHEMBL15281845 | 0.88 | KIF11 (0.49) | KIF11TK1KCNH2SLC6A1SLC6A11 | |
| SCHEMBL16214813 | 0.87 | KIF11 (0.50) | KIF11KCNH2SLC6A1SLC6A11 | |
| SCHEMBL3487683 | 0.87 | KIF11 (0.50) | KIF11KCNH2SLC6A1SLC6A11 | |
| SCHEMBL17357645 | 0.85 | KIF11 (0.44) | KIF11TK1KCNH2SLC6A1SLC6A11 | |
| SCHEMBL24937040 | 0.85 | LMNA (0.46) | KIF11KCNH2SLC6A1SLC6A11MEN1 | |
| SCHEMBL10434091 | 0.85 | LMNA (0.46) | KIF11KCNH2SLC6A1SLC6A11MEN1 | |
| SCHEMBL10434128 | 0.85 | LMNA (0.46) | KIF11KCNH2SLC6A1SLC6A11MEN1 | |
| SCHEMBL1263156 | 0.84 | KIF11 (0.61) | KIF11KCNH2SLC6A1SLC6A11 | |
| SCHEMBL2897015 | 0.84 | KIF11 (0.61) | KIF11KCNH2SLC6A1SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552185-A1 | SYNTHESIS OF OLIGONUCLEOTIDES | ZENECA LIMITED (GB) | 1993-07-28 | — | — | EP | disclosed |
| WO-1992006103-A1 | SYNTHESIS OF OLIGONUCLEOTIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-16 | — | — | WO | disclosed |