⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27296671 | 0.92 | — | — | |
| SCHEMBL9513133 | 0.88 | — | — | |
| SCHEMBL9506370 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL9265163 | 0.87 | — | — | |
| SCHEMBL9268862 | 0.86 | — | — | |
| SCHEMBL9506605 | 0.86 | ATP4A (0.80) | — | |
| SCHEMBL9271993 | 0.85 | — | — | |
| SCHEMBL9267855 | 0.85 | — | — | |
| SCHEMBL9271880 | 0.85 | — | — | |
| SCHEMBL7846181 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0342775-B1 | 4-AMINO-3-ACYLQUINOLINE DERIVATIVES AND THEIR USE AS INHIBITORS OF GASTRIC SECRETION | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1993-09-15 | — | — | EP | claimed |
| US-5143920-A | Antiulcer, antisecretory | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1992-09-01 | — | — | US | claimed |
| EP-0342775-A1 | 4-Amino-3-acylquinoline derivatives and their use as inhibitors of gastric secretion | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1989-11-23 | — | — | EP | claimed |
| CN-1035663-A | The preparation method of the quinoline that replaces | SMITHKLINE BECKMAN INTERCREDIT (NL) | 1989-09-20 | — | — | CN | claimed |
| WO-1989008105-A1 | 4-AMINO-3-ACYLQUINOLINE DERIVATIVES AND THEIR USE AS INHIBITORS OF GASTRIC SECRETION | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1989-09-08 | — | — | WO | claimed |
| EP-0342775-B1 | 4-AMINO-3-ACYLQUINOLINE DERIVATIVES AND THEIR USE AS INHIBITORS OF GASTRIC SECRETION | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1993-09-15 | — | — | EP | disclosed |
| US-5143920-A | Antiulcer, antisecretory | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1992-09-01 | — | — | US | disclosed |
| EP-0342775-A1 | 4-Amino-3-acylquinoline derivatives and their use as inhibitors of gastric secretion | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989008105-A1 | 4-AMINO-3-ACYLQUINOLINE DERIVATIVES AND THEIR USE AS INHIBITORS OF GASTRIC SECRETION | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1989-09-08 | — | — | WO | disclosed |