Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
| ▸ | THRA | P10827 | 10/20 | 0.51 |
| ▸ | THRB | P10828 | 10/20 | 0.51 |
| ▸ | RARB | P10826 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504798 | 0.86 | THRA (0.58) | THRATHRBRARBMEN1ALDH1A1 | |
| SCHEMBL9508859 | 0.86 | THRA (0.61) | THRATHRBRARBMEN1ALDH1A1 | |
| SCHEMBL9504692 | 0.86 | THRA (0.58) | THRATHRBRARBMEN1ALDH1A1 | |
| SCHEMBL9504560 | 0.86 | THRA (0.58) | THRATHRBRARBMEN1ALDH1A1 | |
| SCHEMBL9506907 | 0.85 | THRA (0.56) | THRATHRBRARBMEN1ALDH1A1 | |
| SCHEMBL9508833 | 0.85 | THRA (0.56) | THRATHRBRARBMEN1ALDH1A1 | |
| SCHEMBL9504816 | 0.85 | THRA (0.56) | THRATHRBRARBMEN1ALDH1A1 | |
| SCHEMBL9504727 | 0.85 | THRA (0.56) | THRATHRBRARBMEN1ALDH1A1 | |
| SCHEMBL9504766 | 0.83 | THRA (0.58) | THRATHRBRARBMEN1ALDH1A1 | |
| SCHEMBL10929511 | 0.83 | CYP4Z1 (0.60) | ALOX5THRATHRBRARBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | claimed |
| CN-1012500-B | Process for preparing aryl hydroxamates | SQUIBB & SONS INC (US) | 1991-05-01 | — | — | CN | disclosed |
| CN-85104470-A | The method for preparing arythydroxamtes | — | 1986-10-01 | — | — | CN | disclosed |