Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10469561 | 0.89 | ALDH1A1 (0.51) | ALDH1A1CYP3A4MAPTSMN1; SMN2HSP90AA1 | |
| SCHEMBL269849 | 0.88 | ALDH1A1 (0.66) | ALDH1A1CYP3A4MAPTSMN1; SMN2HSP90AA1 | |
| SCHEMBL12870569 | 0.88 | ALDH1A1 (0.50) | ALDH1A1CYP3A4MAPTSMN1; SMN2HSP90AA1 | |
| SCHEMBL10361043 | 0.87 | HSP90AA1 (0.52) | ALDH1A1CYP3A4MAPTSMN1; SMN2HSP90AA1 | |
| SCHEMBL10545905 | 0.85 | MAPT (0.58) | ALDH1A1CYP3A4MAPTSMN1; SMN2HSP90AA1 | |
| SCHEMBL10747186 | 0.84 | ALDH1A1 (0.47) | ALDH1A1CYP3A4MAPTSMN1; SMN2HSP90AA1 | |
| SCHEMBL10746775 | 0.82 | ALDH1A1 (0.46) | ALDH1A1CYP3A4MAPTSMN1; SMN2HSP90AA1 | |
| SCHEMBL10746965 | 0.82 | ALDH1A1 (0.46) | ALDH1A1CYP3A4MAPTSMN1; SMN2HSP90AA1 | |
| SCHEMBL10512984 | 0.82 | ALDH1A1 (0.59) | ALDH1A1CYP3A4MAPTSMN1; SMN2HSP90AA1 | |
| SCHEMBL6522972 | 0.82 | ALDH1A1 (0.50) | ALDH1A1CYP3A4SMN1; SMN2HSP90AA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051277-B2 | Phenyl(oxy/thio)alkanol derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-09 | — | — | US | claimed |
| US-20140357649-A1 | Phenyl(oxy/thio)alkanol Derivatives | BAYER CROPSCIENCE AG (DE) | 2014-12-04 | — | — | US | claimed |
| EP-2451784-A1 | PHENYL(OXY/THIO)ALKANOL DERIVATIVES | Bayer CropScience AG (DE) | 2012-05-16 | — | — | EP | claimed |
| US-20110039865-A1 | Phenyl(oxy/thio)alkanol Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-02-17 | — | — | US | claimed |
| WO-2011003527-A1 | PHENYL(OXY/THIO)ALKANOL DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-01-13 | — | — | WO | claimed |
| US-9321732-B2 | Phenyl(oxy/thio)alkanol derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-04-26 | — | — | US | disclosed |
| US-9051277-B2 | Phenyl(oxy/thio)alkanol derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-09 | — | — | US | disclosed |
| US-20140357649-A1 | Phenyl(oxy/thio)alkanol Derivatives | BAYER CROPSCIENCE AG (DE) | 2014-12-04 | — | — | US | disclosed |
| US-20110039865-A1 | Phenyl(oxy/thio)alkanol Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140357649-A1 | Phenyl(oxy/thio)alkanol Derivatives | MYB, ALKBH3, OSBP | ALDH1A1 1776/4885CYP3A4 1208/4885MAPT 814/4885 |
| US-20110039865-A1 | Phenyl(oxy/thio)alkanol Derivatives | MYB, ALKBH3, OSBP | ALDH1A1 1776/4885CYP3A4 1208/4885MAPT 814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.