Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10618546 | 0.87 | SLC2A1 (0.50) | SLC2A1KDM1AMAOBTUBB1AOC3 | |
| SCHEMBL698659 | 0.80 | KDM1A (0.46) | SLC2A1KDM1AMAOBAOC3MAOA | |
| SCHEMBL12844281 | 0.78 | SLC2A1 (0.51) | SLC2A1KDM1AMAOBAOC3ALOX5 | |
| SCHEMBL4774241 | 0.78 | AOC3 (0.56) | TUBB1AOC3 | |
| SCHEMBL9579736 | 0.78 | ALOX5 (0.51) | ALOX5PTGS2 | |
| SCHEMBL9786012 | 0.77 | SLC2A1 (0.81) | SLC2A1 | |
| SCHEMBL5712533 | 0.77 | TAAR1 (0.50) | SLC2A1KDM1AMAOBAOC3 | |
| SCHEMBL10617794 | 0.77 | SLC2A1 (0.50) | SLC2A1KDM1AMAOBAOC3MAOA | |
| SCHEMBL5712626 | 0.77 | SLC2A1 (0.50) | SLC2A1KDM1AMAOBAOC3MAOA | |
| SCHEMBL9510475 | 0.76 | AOC3 (0.43) | SLC2A1TUBB1AOC3TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310126-B1 | DERIVATIVES OF PYROCATECHOL-CARBOXYLIC ACID, THEIR PREPARATION AND USE AS ACTIVE INGREDIENTS IN MEDICINES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-08-18 | — | — | EP | disclosed |
| EP-0310126-A2 | Derivatives of pyrocatechol-carboxylic acid, their preparation and use as active ingredients in medicines | F. HOFFMANN-LA ROCHE AG (CH) | 1989-04-05 | — | — | EP | disclosed |