Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 13/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9508786 | 0.94 | ACACB (0.48) | ACACBLMNAKCNH2CYP1A2CYP2D6 | |
| SCHEMBL9511342 | 0.93 | ACACB (0.53) | ACACBLMNAL3MBTL1KCNH2GAA | |
| SCHEMBL11058060 | 0.93 | LMNA (0.50) | ACACBLMNAL3MBTL1KCNH2CYP1A2 | |
| SCHEMBL11058066 | 0.93 | LMNA (0.50) | ACACBLMNAL3MBTL1KCNH2CYP1A2 | |
| SCHEMBL9509403 | 0.92 | ACACB (0.46) | ACACBLMNACYP2D6 | |
| SCHEMBL9508808 | 0.92 | ACACB (0.52) | ACACBLMNAL3MBTL1KCNH2GAA | |
| SCHEMBL10479986 | 0.91 | LMNA (0.49) | ACACBLMNAL3MBTL1KCNH2CYP1A2 | |
| SCHEMBL10479982 | 0.91 | LMNA (0.49) | ACACBLMNAL3MBTL1KCNH2CYP1A2 | |
| SCHEMBL9510199 | 0.91 | ACACB (0.51) | ACACBLMNAL3MBTL1CYP2D6 | |
| SCHEMBL9512430 | 0.90 | ACACB (0.49) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281611-B1 | LIQUID CRYSTAL PHASES FOR ELECTRO-OPTIC DISPLAY ELEMENTS BASED ON THE ECB EFFECT | MERCK PATENT GMBH (DE) | 1993-11-24 | — | — | EP | disclosed |
| EP-0308438-B1 | LIQUID CRYSTAL PHASE CONTAINING TOLANES | MERCK PATENT GmbH (DE) | 1993-09-29 | — | — | EP | disclosed |
| EP-0281611-A1 | LIQUID CRYSTAL PHASES FOR ELECTRO-OPTIC DISPLAY ELEMENTS BASED ON THE ECB EFFECT. | MERCK PATENT GMBH (DE) | 1988-09-14 | — | — | EP | disclosed |