Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11058066 | 1.00 | LMNA (0.50) | LMNAL3MBTL1KCNH2CYP1A2CYP2D6 | |
| SCHEMBL10479986 | 0.98 | LMNA (0.49) | LMNAL3MBTL1KCNH2CYP1A2CYP2D6 | |
| SCHEMBL10479982 | 0.98 | LMNA (0.49) | LMNAL3MBTL1KCNH2CYP1A2CYP2D6 | |
| SCHEMBL10718213 | 0.95 | LMNA (0.47) | LMNAL3MBTL1KCNH2CYP1A2CYP2D6 | |
| SCHEMBL10900495 | 0.94 | KMT2A (0.48) | LMNAL3MBTL1KCNH2CYP1A2CYP2D6 | |
| SCHEMBL10900503 | 0.94 | KMT2A (0.48) | LMNAL3MBTL1KCNH2CYP1A2CYP2D6 | |
| SCHEMBL9509255 | 0.93 | ACACB (0.54) | LMNAL3MBTL1KCNH2CYP1A2CYP2D6 | |
| SCHEMBL10479580 | 0.92 | KMT2A (0.47) | LMNAL3MBTL1KCNH2CYP1A2CYP2D6 | |
| SCHEMBL9345132 | 0.92 | HRH3 (0.49) | LMNAL3MBTL1KCNH2CYP2D6ALDH1A1 | |
| SCHEMBL10479583 | 0.92 | KMT2A (0.47) | LMNAL3MBTL1KCNH2CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439015-A | Disubstituted ethanes | HOFFMANN-LA ROCHE INC. (US) | 1984-03-27 | — | — | US | disclosed |