SCHEMBL9509313

SCHEMBL9509313

Cc1ccc(-c2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.45
GAA P10253 1/20 0.45
TDP1 Q9NUW8 2/20 0.44
TP53 P04637 1/20 0.44
RAPGEF4 Q8WZA2 4/20 0.41
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2A6 P11509 2/20 0.39
ALDH1A1 P00352 2/20 0.39
ELANE P08246 1/20 0.38
LMNA P02545 1/20 0.38
ALPL P05186 1/20 0.38
CA9 Q16790 1/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
NQO1 P15559 2/20 0.36
POR P16435 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31049807 0.85 PDK2 (0.46) MAPTGAATDP1TP53MAOA
SCHEMBL3043421 0.83 TDP1 (0.52) MAPTGAATDP1TP53RAPGEF4
SCHEMBL31547677 0.83 TDP1 (0.52) MAPTGAATDP1TP53RAPGEF4
SCHEMBL28713658 0.82 RAPGEF4 (0.43) MAPTGAATDP1TP53RAPGEF4
SCHEMBL11588315 0.80 GAA (0.52) MAPTGAATDP1TP53MAOA
SCHEMBL6932113 0.78 TDP1 (0.52) MAPTGAATDP1TP53ALDH1A1
SCHEMBL10853627 0.78 RAPGEF4 (0.41) RAPGEF4
SCHEMBL29038580 0.78 MAPT (0.48) MAPTGAATDP1TP53RAPGEF4
SCHEMBL4265966 0.77 PDK2 (0.44) GAATP53CYP1A2CYP2A6ALDH1A1
SCHEMBL25813777 0.77 MAPT (0.44) MAPTGAATDP1TP53RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0333415-B1 AN ELECTROPHOTOGRAPHIC LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJI PHOTO FILM CO., LTD. (JP) 1993-09-22 EP disclosed
US-5053301-A Zinc oxide, resin binder, hydrophilic resin grains FUJI PHOTO FILM CO., LTD. (JP) 1991-10-01 US disclosed
EP-0333415-A2 An electrophotographic lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 1989-09-20 EP disclosed