Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5666158 | 0.86 | DHFR (0.41) | TDP1CYP3A4SMN1; SMN2ALOX15TP53 | |
| SCHEMBL2934180 | 0.79 | ALDH1A1 (0.46) | TDP1CYP3A4SMN1; SMN2ALOX15TP53 | |
| SCHEMBL31049807 | 0.79 | PDK2 (0.46) | TDP1CYP3A4SMN1; SMN2ALOX15TP53 | |
| SCHEMBL9509313 | 0.78 | MAPT (0.45) | TDP1SMN1; SMN2TP53ALDH1A1MAPT | |
| SCHEMBL33980 | 0.78 | — | — | |
| SCHEMBL29366708 | 0.78 | — | — | |
| SCHEMBL3043421 | 0.77 | TDP1 (0.52) | TDP1CYP3A4SMN1; SMN2ALOX15TP53 | |
| SCHEMBL31547677 | 0.77 | TDP1 (0.52) | TDP1CYP3A4SMN1; SMN2ALOX15TP53 | |
| Ammonia Solution, Strong SCHEMBL1548755 | 0.75 | TDP1 (0.62) | TDP1CYP3A4SMN1; SMN2ALOX15TP53 | |
| Fluoride SCHEMBL18789317 | 0.75 | TDP1 (0.62) | TDP1CYP3A4SMN1; SMN2ALOX15TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186595-B1 | Diaryl-p-phenylenediamine disulfides | GOODYEAR TIRE & RUBBER (US) | 2003-11-26 | — | — | EP | disclosed |
| US-6627686-B1 | Mixture with rubber; oxidation resistance; tires, rolls, conveyor belts, footwear | THE GOODYEAR TIRE & RUBBER COMPANY | 2003-09-30 | — | — | US | disclosed |
| EP-1186595-A1 | Diaryl-p-phenylenediamine disulfides | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2002-03-13 | — | — | EP | disclosed |
| EP-0700963-B1 | Polymeric N-aryl substituted and N-alkaryl substituted diphenyldiamines | GOODYEAR TIRE & RUBBER (US) | 1999-04-14 | — | — | EP | disclosed |
| US-5726248-A | ANTIOXIDANTS FOR DIENE POLYMERS WITH HIGH MOLECULAR WEIGHTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| EP-0700963-A1 | Polymeric N-aryl substituted and N-alkaryl substituted diphenyldiamines | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1996-03-13 | — | — | EP | disclosed |