Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | IL1RN | P18510 | 1/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | LAP3 | P28838 | 2/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.46 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2520851 | 1.00 | MME (0.49) | MMECA2CA1IL1RNERAP2 | |
| SCHEMBL7431625 | 0.88 | MME (0.55) | MMEIL1RNERAP2LTA4HFOLH1 | |
| SCHEMBL10509294 | 0.86 | FOLH1 (0.64) | MMEIL1RNERAP2LTA4HFOLH1 | |
| SCHEMBL29674545 | 0.86 | FOLH1 (0.64) | MMEIL1RNERAP2LTA4HFOLH1 | |
| SCHEMBL10509278 | 0.86 | FOLH1 (0.64) | MMEIL1RNERAP2LTA4HFOLH1 | |
| SCHEMBL7431310 | 0.86 | MME (0.53) | MMEIL1RNERAP2LTA4HFOLH1 | |
| SCHEMBL7431301 | 0.86 | MME (0.53) | MMEIL1RNERAP2LTA4HFOLH1 | |
| SCHEMBL7440911 | 0.86 | MME (0.53) | MMEIL1RNERAP2LTA4HFOLH1 | |
| Ubenimex SCHEMBL5812930 | 0.86 | MME (0.66) | MMELTA4HLAP3ANPEPRNPEP | |
| Ubenimex SCHEMBL16782425 | 0.86 | MME (0.66) | MMELTA4HLAP3ANPEPRNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028626-A | Peptides with pharmaceutical activity | ZAMBON GROUP S.P.A. (IT) | 1991-07-02 | — | — | US | claimed |
| EP-0332999-B1 | PEPTIDES WITH INHIBITORY ACTIVITY OF ENZYMATIC SYSTEMS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.p.A. (IT) | 1993-09-29 | — | — | EP | disclosed |
| US-5028626-A | Peptides with pharmaceutical activity | ZAMBON GROUP S.P.A. (IT) | 1991-07-02 | — | — | US | disclosed |
| EP-0332999-A2 | Peptides with inhibitory activity of enzymatic systems, process for their preparation and pharmaceutical compositions containing them | ZAMBON GROUP S.p.A. (IT) | 1989-09-20 | — | — | EP | disclosed |