Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8760301 | 0.83 | ESR1 (0.52) | ALDH1A1TSHRHDAC8MAPTESR1 | |
| SCHEMBL28846222 | 0.83 | ALDH1A1 (0.50) | ALDH1A1TSHRHDAC8MAPTESR1 | |
| SCHEMBL16341162 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TSHRHDAC8MAPTESR1 | |
| SCHEMBL15698321 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TSHRHDAC8MAPTESR1 | |
| SCHEMBL619307 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TSHRHDAC8MAPTESR1 | |
| SCHEMBL28846186 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TSHRHDAC8MAPTESR1 | |
| SCHEMBL10523793 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TSHRHDAC8MAPTESR1 | |
| SCHEMBL9715846 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TSHRHDAC8MAPTESR1 | |
| SCHEMBL15807759 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TSHRHDAC8MAPTESR1 | |
| SCHEMBL10626255 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TSHRHDAC8MAPTESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5004993-A | — | — | None | — | — | JP | disclosed |
| JP-H054993-A | SILICON-CONTAINING COMPOUND | HOECHST JAPAN LTD | 1993-01-14 | — | — | JP | disclosed |