Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 5/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24059372 | 0.95 | JAK3 (0.51) | JAK3ATMTRPV1MAPTTDP1 | |
| SCHEMBL19227318 | 0.84 | ALDH1A1 (0.50) | JAK3ATMTRPV1MEN1KMT2A | |
| SCHEMBL20733138 | 0.84 | ALDH1A1 (0.50) | JAK3ATMTRPV1MEN1KMT2A | |
| SCHEMBL20733110 | 0.84 | ALDH1A1 (0.50) | JAK3ATMTRPV1MEN1KMT2A | |
| SCHEMBL182620 | 0.84 | ALDH1A1 (0.50) | JAK3ATMTRPV1MEN1KMT2A | |
| SCHEMBL19227252 | 0.84 | ALDH1A1 (0.50) | JAK3ATMTRPV1MEN1KMT2A | |
| SCHEMBL1498684 | 0.83 | ALDH1A1 (0.46) | JAK3ATMMAPTTDP1LMNA | |
| SCHEMBL11693073 | 0.82 | ALDH1A1 (0.47) | JAK3ATMTRPV1MAPTLMNA | |
| SCHEMBL4485887 | 0.82 | HRH4 (0.44) | JAK3ATMTRPV1MEN1KMT2A | |
| SCHEMBL9514566 | 0.81 | ATM (0.43) | JAK3ATMTRPV1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446554-B1 | PREPARATION OF A N-SUBSTITUTED PHENYLENEDIAMINE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-10-13 | — | — | EP | disclosed |
| US-5068439-A | Chemical intermediates for dyes, drugs, agricultural products and as antoxidants or stabilizers for rubbers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-11-26 | — | — | US | disclosed |
| EP-0446554-A1 | Preparation of a N-substituted phenylenediamine | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-09-18 | — | — | EP | disclosed |
| US-4968843-A | FROM 4-HYDROXYDIPHENYLAMINE; EXCELLENT YIELDS OF HIGH PURITY | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1990-11-06 | — | — | US | disclosed |