SCHEMBL9514566

SCHEMBL9514566

CCN(c1ccc(Nc2ccc(Nc3ccccc3)cc2)cc1)C1CCCCCCCCCCC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 3/20 0.43
JAK3 P52333 1/20 0.43
TDP1 Q9NUW8 3/20 0.42
GAA P10253 3/20 0.42
MAPT P10636 3/20 0.42
MAPK1 P28482 2/20 0.42
MEN1 O00255 2/20 0.42
LMNA P02545 2/20 0.42
KMT2A Q03164 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
L3MBTL1 Q9Y468 3/20 0.41
ALDH1A1 P00352 2/20 0.41
ALOX15 P16050 2/20 0.41
TSHR P16473 2/20 0.41
ALOX12 P18054 2/20 0.41
HSD17B10 Q99714 2/20 0.41
PTGS1 P23219 1/20 0.41
SLC6A2 P23975 1/20 0.41
PTGS2 P35354 1/20 0.41
HTR2B P41595 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9513121 1.00 ATM (0.43) ATMJAK3TDP1GAAMAPT
SCHEMBL9514252 0.94 RAB9A (0.43) JAK3MEN1LMNAKMT2ASMN1; SMN2
SCHEMBL11691432 0.87 L3MBTL1 (0.46) ATMGAAMEN1KMT2ASMN1; SMN2
SCHEMBL11069272 0.85 CHRM1 (0.46) MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL4484272 0.85 ADH1C (0.41) GAAMEN1KMT2AL3MBTL1TRPV1
SCHEMBL4474636 0.85 ADH1C (0.41) GAAMEN1KMT2AL3MBTL1TRPV1
SCHEMBL4483045 0.81 LMNA (0.41) TDP1GAAMAPTMAPK1MEN1
SCHEMBL9509525 0.81 JAK3 (0.55) ATMJAK3TDP1GAAMAPT
SCHEMBL1498684 0.80 ALDH1A1 (0.46) ATMJAK3TDP1GAAMAPT
SCHEMBL1498762 0.80 KMT2A (0.41) ATMJAK3TDP1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0273418-B1 Heat-sensitive recording material using chromeno compound KANZAKI PAPER MFG CO LTD (JP) 1993-11-24 EP disclosed
US-4803193-A COLORFASTNESS; READABLE BY OPTICAL CHARACTER-READING DEVICES KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1989-02-07 US disclosed
EP-0273418-A2 Heat-sensitive recording material using chromeno compound KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-07-06 EP disclosed