Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 5/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | RECQL | P46063 | 3/20 | 0.59 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.59 |
| ▸ | APEX1 | P27695 | 3/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.59 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.59 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5121214 | 1.00 | BLM (0.59) | BLMTDP1KDM4EMAPTRECQL | |
| SCHEMBL15061878 | 0.81 | BLM (0.65) | BLMTDP1KDM4EMAPTRECQL | |
| SCHEMBL7152531 | 0.80 | ADRB2 (0.67) | BLMTDP1KDM4EMAPTRECQL | |
| SCHEMBL2852257 | 0.80 | ADRB2 (0.67) | BLMTDP1KDM4EMAPTRECQL | |
| L-Norepinephrine SCHEMBL10427349 | 0.78 | BLM (0.82) | BLMTDP1KDM4EMAPTRECQL | |
| Norepinephrine SCHEMBL9659883 | 0.78 | BLM (0.82) | BLMTDP1KDM4EMAPTRECQL | |
| Norepinephrine SCHEMBL9659319 | 0.78 | BLM (0.82) | BLMTDP1KDM4EMAPTRECQL | |
| L-Norepinephrine SCHEMBL9659893 | 0.78 | BLM (0.82) | BLMTDP1KDM4EMAPTRECQL | |
| L-Norepinephrine SCHEMBL9659315 | 0.78 | BLM (0.82) | BLMTDP1KDM4EMAPTRECQL | |
| Norepinephrine SCHEMBL10427348 | 0.78 | BLM (0.82) | BLMTDP1KDM4EMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322164-B1 | ETHANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1993-09-22 | — | — | EP | disclosed |
| US-5039697-A | Adrenergic stimulants, bronchodilators | GLAXO GROUP LIMITED (GB) | 1991-08-13 | — | — | US | disclosed |
| US-5032609-A | Ethanolamine derivatives | GLAXO GROUP LIMITED (GB) | 1991-07-16 | — | — | US | disclosed |
| US-5002966-A | Adrenergic Stimulants | GLAXO GROUP LIMITED (GB) | 1991-03-26 | — | — | US | disclosed |
| US-4963564-A | ADRENERGIC STIMULANTS | GLAXO GROUP LTD. (GB) | 1990-10-16 | — | — | US | disclosed |
| EP-0322164-A2 | Ethanolamine derivatives | GLAXO GROUP LIMITED (GB) | 1989-06-28 | — | — | EP | disclosed |
| EP-0303465-A2 | Phenethanolamine derivatives | GLAXO GROUP LIMITED (GB) | 1989-02-15 | — | — | EP | disclosed |