Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9507506 | 0.80 | MAPT (0.36) | TSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL3904364 | 0.80 | TSHR (0.44) | TSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6734968 | 0.80 | TSHR (0.44) | TSHRALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6734970 | 0.80 | TSHR (0.44) | TSHRALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9507272 | 0.80 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL25634926 | 0.79 | TSHR (0.37) | TSHRALDH1A1 | |
| SCHEMBL6741137 | 0.78 | TSHR (0.42) | TSHRALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6741133 | 0.78 | ALDH1A1 (0.42) | TSHRALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9509857 | 0.77 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2GABRR1CYP1A2 | |
| SCHEMBL129604 | 0.77 | TSHR (0.50) | TSHRALDH1A1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388960-B1 | OPTICALLY ACTIVE COMPOUNDS AND THEIR PREPARATION AND USE | HITACHI, LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5152919-A | Stability, chemical resistance, high speed response, large spo ntaneous polarization, molecular orientation and wide temperat ure range | HITACHI, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0388960-A1 | Optically active compounds and their preparation and use | HITACHI, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |