Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ESRRB | O95718 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7105090 | 0.90 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2CA1CA2CA14 | |
| SCHEMBL19526547 | 0.84 | SMN1; SMN2 (0.38) | SMN1; SMN2CA1CA2CA14ZDHHC7 | |
| SCHEMBL7707505 | 0.83 | SMN1; SMN2 (0.41) | SMN1; SMN2CA1CA2CA14ZDHHC7 | |
| SCHEMBL13640440 | 0.80 | CA1 (0.45) | SMN1; SMN2CA1CA2CA14ZDHHC7 | |
| SCHEMBL9507272 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KMT2A | |
| SCHEMBL9507980 | 0.79 | ALDH1A1 (0.39) | ALDH1A1GABRR1CYP1A2 | |
| SCHEMBL19783671 | 0.79 | ZDHHC7 (0.42) | ALDH1A1SMN1; SMN2CA1CA2CA14 | |
| SCHEMBL1367718 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2CA1CA2CA14ZDHHC7 | |
| SCHEMBL27980156 | 0.79 | CHRNB2 (0.38) | SMN1; SMN2CA1CA2CA14ZDHHC7 | |
| SCHEMBL12764098 | 0.78 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2CA1CA2CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388960-B1 | OPTICALLY ACTIVE COMPOUNDS AND THEIR PREPARATION AND USE | HITACHI, LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5152919-A | Stability, chemical resistance, high speed response, large spo ntaneous polarization, molecular orientation and wide temperat ure range | HITACHI, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0388960-A1 | Optically active compounds and their preparation and use | HITACHI, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |