Dimethylamine

Dimethylamine

SCHEMBL9509849

CNC.O=C1C(=Cc2ccccc2)CCC1=Cc1ccccc1

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.84
F3 P13726 1/20 0.71
MAOB P27338 3/20 0.61
MGAM O43451 3/20 0.59
GAA P10253 3/20 0.59
SI P14410 3/20 0.59
MGAM2 Q2M2H8 3/20 0.59
MAPT P10636 4/20 0.58
ALDH1A1 P00352 4/20 0.58
LMNA P02545 2/20 0.58
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
EGFR P00533 1/20 0.55
HSD11B1 P28845 2/20 0.55
CYP3A4 P08684 1/20 0.55
CYP2C9 P11712 1/20 0.55
HTT P42858 1/20 0.53
MIF P14174 2/20 0.53
NPC1 O15118 1/20 0.51
POLB P06746 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,6-Dibenzylidenecyclohexanone SCHEMBL5688633 0.92 CYP1A2 (0.85) CYP1A2F3MGAMGAASI
SCHEMBL3128602 0.92 CYP1A2 (1.00) CYP1A2F3MAOBMGAMGAA
SCHEMBL23633272 0.92 CYP1A2 (1.00) CYP1A2F3MAOBMGAMGAA
SCHEMBL12948629 0.92 CYP1A2 (1.00) CYP1A2F3MAOBMGAMGAA
SCHEMBL978681 0.92 CYP1A2 (1.00) CYP1A2F3MAOBMGAMGAA
Diethylamine SCHEMBL5688882 0.85 CYP1A2 (0.72) CYP1A2F3MAOBMGAMGAA
Dimethylamine SCHEMBL9633966 0.85 CYP1A2 (0.60) CYP1A2F3MAOBMGAMGAA
SCHEMBL3263383 0.83 CYP1A2 (0.92) CYP1A2F3MAOBMGAMGAA
2,6-Dibenzylidenecyclohexanone SCHEMBL12948726 0.83 CYP1A2 (1.00) CYP1A2F3MAOBMGAMGAA
2,6-Dibenzylidenecyclohexanone SCHEMBL977260 0.83 CYP1A2 (1.00) CYP1A2F3MAOBMGAMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0364120-B1 A CYCLOALKENE COMPOUND AND A RECORDING MATERIAL USING THE COMPOUND HODOGAYA CHEMICAL COMPANY, LIMITED (JP) 1993-08-11 EP disclosed
US-4987262-A Absorbers of near infrared radiation, chromogens HODOGAYA CHEMICAL CO., LTD. (JP) 1991-01-22 US disclosed
EP-0364120-A2 A cycloalkene compound and a recording material using the compound HODOGAYA CHEMICAL COMPANY, LIMITED (JP) 1990-04-18 EP disclosed