SCHEMBL3128602

SCHEMBL3128602

O=C1/C(=C\c2ccccc2)CC/C1=C\c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 1.00
F3 P13726 1/20 0.83
MAOB P27338 5/20 0.69
MGAM O43451 3/20 0.67
GAA P10253 3/20 0.67
SI P14410 3/20 0.67
MGAM2 Q2M2H8 3/20 0.67
HSD11B1 P28845 2/20 0.63
CYP3A4 P08684 1/20 0.63
CYP2C9 P11712 1/20 0.63
ALDH1A1 P00352 4/20 0.61
HTT P42858 1/20 0.61
MAPT P10636 4/20 0.61
LMNA P02545 2/20 0.61
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
MIF P14174 2/20 0.59
EGFR P00533 1/20 0.57
NPC1 O15118 1/20 0.57
POLB P06746 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12948629 1.00 CYP1A2 (1.00) CYP1A2F3MAOBMGAMGAA
SCHEMBL23633272 1.00 CYP1A2 (1.00) CYP1A2F3MAOBMGAMGAA
SCHEMBL978681 1.00 CYP1A2 (1.00) CYP1A2F3MAOBMGAMGAA
Dimethylamine SCHEMBL9509849 0.92 CYP1A2 (0.84) CYP1A2F3MAOBMGAMGAA
2,6-Dibenzylidenecyclohexanone SCHEMBL977260 0.91 CYP1A2 (1.00) CYP1A2F3MAOBMGAMGAA
2,6-Dibenzylidenecyclohexanone SCHEMBL12948726 0.91 CYP1A2 (1.00) CYP1A2F3MAOBMGAMGAA
SCHEMBL3263387 0.91 CYP1A2 (0.92) CYP1A2F3MAOBMGAMGAA
2,6-Dibenzylidenecyclohexanone SCHEMBL977261 0.91 CYP1A2 (1.00) CYP1A2F3MAOBMGAMGAA
SCHEMBL3263383 0.91 CYP1A2 (0.92) CYP1A2F3MAOBMGAMGAA
2,6-Dibenzylidenecyclohexanone SCHEMBL11732500 0.89 CYP1A2 (0.96) CYP1A2F3MAOBMGAMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016181220-A2 THERAPEUTIC COMPOSITIONS AND METHODS OF USE THEREOF IONS PHARMACEUTICAL S.À R.L. (LU) 2016-11-17 WO claimed
US-7166274-B2 Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds L'OREAL (FR) 2007-01-23 US claimed
US-20040047820-A1 Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds SOCIETE L'OREAL S.A. (FR) 2004-03-11 US claimed
EP-1370232-A2 COSMETIC SOLAR PROTECTION COMPOSITIONS BASED ON A SYNERGIC MIXTURE OF FILTERS AND USES L'OREAL (FR) 2003-12-17 EP claimed
US-6627180-B2 Particles having protection factor UV-APPD and an amino substituted 2-hydroxybenzophenone SOCIETE L'OREAL S.A. (FR) 2003-09-30 US claimed
US-20030152532-A1 SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS SOCIETE L'OREAL S.A. (FR) 2003-08-14 US claimed
EP-1317918-A1 Cosmetic sunscreen compositions based on synergistic filter mixture and their use L'OREAL (FR) 2003-06-11 EP claimed
WO-2002056858-A1 SOLAR PROTECTION COMPOSITIONS L'OREAL (FR) 2002-07-25 WO claimed
WO-2002049597-A2 COSMETIC SOLAR PROTECTION COMPOSITIONS BASED ON A SYNERGIC MIXTURE OF FILTERS AND USES L'OREAL (FR) 2002-06-27 WO claimed
EP-3709966-B1 COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT OREAL (FR) 2024-12-11 EP disclosed
US-20210346249-A1 COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER L'OREAL (FR) 2021-11-11 US disclosed
EP-3185843-B1 GEL COMPOSITION AND GEL COMPRISING A UV FILTER OREAL (FR) 2021-08-11 EP disclosed
EP-2872107-B1 COSMETIC COMPOSITION CONTAINING SCREENING COMPOSITE PARTICLES OREAL (FR) 2021-07-21 EP disclosed
US-20200360264-A1 COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT L'OREAL (FR) 2020-11-19 US disclosed
EP-1281391-A1 Organic insoluble UV filters of the aryl vinylene ketone type and their use in cosmetics L'OREAL (FR) 2003-02-05 EP disclosed
WO-2002056858-A1 SOLAR PROTECTION COMPOSITIONS L'OREAL (FR) 2002-07-25 WO disclosed
WO-2002049597-A2 COSMETIC SOLAR PROTECTION COMPOSITIONS BASED ON A SYNERGIC MIXTURE OF FILTERS AND USES L'OREAL (FR) 2002-06-27 WO disclosed
EP-0538112-B1 Electrophotographic photosensitive member, electrophotographic apparatus, device unit and facsimile machine CANON KK (JP) 1997-12-29 EP disclosed
US-5356746-A Containing triazine compound CANON KABUSHIKI KAISHA (JP) 1994-10-18 US disclosed
EP-0538112-A1 Electrophotographic photosensitive member, electrophotographic apparatus, device unit and facsimile machine CANON KABUSHIKI KAISHA (JP) 1993-04-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200360264-A1 COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT PCNA, ERCC1, XRCC6 CYP1A2 4136/4885F3 3389/4885MAOB 3621/4885
US-20040047820-A1 Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds SUCLG1, CUTA, DLD CYP1A2 1004/4885F3 3415/4885MAOB 1776/4885
US-20210346249-A1 COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER ERCC5, CUTA, PLIN5 CYP1A2 3204/4885F3 2308/4885MAOB 2456/4885
US-20030152532-A1 SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS HADHB, SDHA, ERCC4 CYP1A2 738/4885F3 3717/4885MAOB 1274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.