Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | MEN1 | O00255 | 8/20 | 0.52 |
| ▸ | RAB9A | P51151 | 8/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.47 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.47 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL270426 | 0.82 | MEN1 (0.66) | MAPTMEN1RAB9AKMT2AALDH1A1 | |
| SCHEMBL270425 | 0.82 | MEN1 (0.66) | MAPTMEN1RAB9AKMT2AALDH1A1 | |
| SCHEMBL29588234 | 0.82 | MEN1 (0.66) | MAPTMEN1RAB9AKMT2AALDH1A1 | |
| SCHEMBL3261324 | 0.82 | MEN1 (0.53) | MAPTMEN1RAB9AKMT2AALDH1A1 | |
| SCHEMBL3261323 | 0.82 | MEN1 (0.53) | MAPTMEN1RAB9AKMT2AALDH1A1 | |
| SCHEMBL9787130 | 0.81 | CYP19A1 (0.54) | MAPTMEN1RAB9AKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL28545676 | 0.81 | MEN1 (0.64) | MAPTMEN1RAB9AKMT2AALDH1A1 | |
| Methane SCHEMBL5133892 | 0.81 | ALDH1A1 (0.64) | MAPTMEN1RAB9AKMT2AALDH1A1 | |
| Acrylic Acid SCHEMBL29013835 | 0.80 | ALDH1A1 (0.53) | MAPTMEN1RAB9AKMT2AALDH1A1 | |
| SCHEMBL887522 | 0.77 | MEN1 (0.60) | MAPTMEN1RAB9AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350112-B1 | POLYURETHANES PREPARED FROM NON-LINEAR OPTICAL ACTIVE DIOLS | Akzo Nobel N.V. (NL) | 1993-10-06 | — | — | EP | disclosed |
| US-5001209-A | Non-linear optical active diols and polyurethanes prepared therefrom | AKZO N.V. (NL) | 1991-03-19 | — | — | US | disclosed |
| EP-0350112-A1 | Polyurethanes prepared from non-linear optical active diols | Akzo Nobel N.V. (NL) | 1990-01-10 | — | — | EP | disclosed |