SCHEMBL887522

SCHEMBL887522

O=[N+]([O-])c1ccc(-c2ccc(N=Nc3ccccc3)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.60
KMT2A Q03164 7/20 0.60
ALDH1A1 P00352 6/20 0.60
RAB9A P51151 5/20 0.60
MAPT P10636 5/20 0.60
MAPK1 P28482 4/20 0.60
SMN1; SMN2 Q16637 3/20 0.60
CASP3 P42574 1/20 0.60
SENP8 Q96LD8 1/20 0.60
SENP7 Q9BQF6 1/20 0.60
SENP6 Q9GZR1 1/20 0.60
NPC1 O15118 4/20 0.57
TNNI3 P19429 1/20 0.57
TNNT2 P45379 1/20 0.57
TNNC1 P63316 1/20 0.57
KEAP1 Q14145 1/20 0.57
NFE2L2 Q16236 1/20 0.57
POLB P06746 3/20 0.56
LMNA P02545 2/20 0.56
TDP1 Q9NUW8 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29588234 0.94 MEN1 (0.66) MEN1KMT2AALDH1A1RAB9AMAPT
SCHEMBL270426 0.94 MEN1 (0.66) MEN1KMT2AALDH1A1RAB9AMAPT
SCHEMBL270425 0.94 MEN1 (0.66) MEN1KMT2AALDH1A1RAB9AMAPT
Methane SCHEMBL5133892 0.92 ALDH1A1 (0.64) MEN1KMT2AALDH1A1RAB9AMAPT
Hydrochloric Acid SCHEMBL28545676 0.92 MEN1 (0.64) MEN1KMT2AALDH1A1RAB9AMAPT
Azobenzene SCHEMBL28643957 0.88 ALDH1A1 (0.73) MEN1KMT2AALDH1A1RAB9AMAPT
SCHEMBL27083975 0.87 MEN1 (0.58) MEN1KMT2AALDH1A1RAB9AMAPT
SCHEMBL27137343 0.87 MEN1 (0.58) MEN1KMT2AALDH1A1RAB9AMAPT
SCHEMBL3282773 0.85 MEN1 (0.61) MEN1KMT2AALDH1A1RAB9AMAPT
SCHEMBL3282776 0.85 MEN1 (0.61) MEN1KMT2AALDH1A1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114381003-A Preparation and application of fluorine-containing polyimide/inorganic oxide hybrid material 苏州聚萃材料科技有限公司 2022-04-22 CN claimed
CN-114381003-A Preparation and application of fluorine-containing polyimide/inorganic oxide hybrid material 苏州聚萃材料科技有限公司 2022-04-22 CN disclosed
US-8067177-B2 Amplification methods EPOCH BIOSCIENCES, INC. (US) 2011-11-29 US disclosed
US-8067177-B2 Amplification methods EPOCH BIOSCIENCES, INC. (US) 2011-11-29 US disclosed
US-7897736-B2 Fluorescent quenching detecting reagents and methods ELITECH HOLDING B.V. (NL) 2011-03-01 US disclosed
US-7897736-B2 Fluorescent quenching detecting reagents and methods ELITECH HOLDING B.V. (NL) 2011-03-01 US disclosed
US-20110027780-A1 AMPLIFICATION METHODS ELITECHGROUP MDX LLC 2011-02-03 US disclosed
US-20110027780-A1 AMPLIFICATION METHODS ELITECHGROUP MDX LLC 2011-02-03 US disclosed
US-7759126-B2 Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for amplification (or PCR) analysis ELITECH HOLDING B.V. (NL) 2010-07-20 US disclosed
US-7759126-B2 Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for amplification (or PCR) analysis ELITECH HOLDING B.V. (NL) 2010-07-20 US disclosed
US-20080248474-A1 AMPLIFICATION METHODS EPOCH BIOSCIENCES, INC (US) 2008-10-09 US disclosed
US-20080248474-A1 AMPLIFICATION METHODS EPOCH BIOSCIENCES, INC (US) 2008-10-09 US disclosed
US-7381818-B2 Fluorescent probes containing 5′-minor groove binder, fluorophore and quenching moieties and methods of use thereof EPOCH BIOSCIENCES, INC. (US) 2008-06-03 US disclosed
US-7381818-B2 Fluorescent probes containing 5′-minor groove binder, fluorophore and quenching moieties and methods of use thereof EPOCH BIOSCIENCES, INC. (US) 2008-06-03 US disclosed
US-7319022-B1 Amplification and monitoring of oligonucleotide amplification in which a primer has an overlap with one or more bases of a detection probe EPOCH BIOSCIENCES, INC. (US) 2008-01-15 US disclosed
US-7319022-B1 Amplification and monitoring of oligonucleotide amplification in which a primer has an overlap with one or more bases of a detection probe EPOCH BIOSCIENCES, INC. (US) 2008-01-15 US disclosed
US-7205105-B2 Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for PCR analysis EPOCH BIOSCIENCES, INC. (US) 2007-04-17 US disclosed
US-7205105-B2 Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for PCR analysis EPOCH BIOSCIENCES, INC. (US) 2007-04-17 US disclosed
US-20070003957-A1 Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis EPOCH BIOSCIENCES, INC. (US) 2007-01-04 US disclosed
US-20070003957-A1 Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis EPOCH BIOSCIENCES, INC. (US) 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070003957-A1 Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis RNGTT, DCLRE1B, CNBP MEN1 3439/4885KMT2A 2455/4885ALDH1A1 3606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.