Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12247723 | 0.78 | L3MBTL1 (0.50) | L3MBTL1NPC1ALDH1A1CYP2C9HPGD | |
| SCHEMBL9814781 | 0.77 | MAPT (0.53) | MCL1POLBGAAHSD17B10MAPT | |
| SCHEMBL8159995 | 0.77 | MCL1 (0.51) | MCL1POLBGAAHSD17B10MAPT | |
| SCHEMBL11519541 | 0.76 | MCL1 (0.76) | MCL1POLBGAAHSD17B10MAPT | |
| SCHEMBL12789408 | 0.74 | HTR2A (0.49) | MCL1ALDH1A1MEN1KMT2A | |
| SCHEMBL749191 | 0.73 | MCL1 (0.89) | MCL1POLBGAAHSD17B10MAPT | |
| SCHEMBL10503967 | 0.72 | MCL1 (0.47) | MCL1POLBGAAHSD17B10MAPT | |
| SCHEMBL19751086 | 0.71 | RIPK1 (0.47) | MCL1EPHX1MEN1KMT2A | |
| SCHEMBL600072 | 0.71 | MCL1 (1.00) | MCL1POLBGAAHSD17B10MAPT | |
| SCHEMBL29287392 | 0.70 | MCL1 (0.57) | MCL1POLBGAAHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298680-B1 | HERBICIDAL COMPOSITIONS OF ACYLATED 1,3-DICARBONYL HERBICIDES AND ANTIDOTES THEREFOR | ZENECA INC. (US) | 1993-09-15 | — | — | EP | disclosed |
| US-4938796-A | Haloalkamides and naphthalene anhydride | ICI AMERICAS INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4859234-A | Herbicidal compositions of acylated 1,3-dicarbonyl herbicides and phenoxyalkanoic acids, salts, amides and esters therof as antidotes | ICI AMERICAS INC. (US) | 1989-08-22 | — | — | US | disclosed |
| EP-0298680-A2 | Herbicidal compositions of acylated 1,3-dicarbonyl herbicides and antidotes therefor | ZENECA INC. (US) | 1989-01-11 | — | — | EP | disclosed |
| US-4695673-A | Process for the production of acylated 1,3-dicarbonyl compounds | STAUFFER CHEMICAL COMPANY (US) | 1987-09-22 | — | — | US | disclosed |