Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9723911 | 0.86 | MEN1 (0.48) | MEN1KMT2A | |
| SCHEMBL9652797 | 0.85 | ATP4A (0.50) | — | |
| SCHEMBL9265136 | 0.85 | MEN1 (0.46) | MEN1KMT2A | |
| SCHEMBL9506558 | 0.84 | MEN1 (0.45) | MEN1KMT2A | |
| SCHEMBL9267772 | 0.83 | MEN1 (0.44) | MEN1KMT2A | |
| SCHEMBL774957 | 0.82 | ATP4A (0.61) | — | |
| SCHEMBL9723921 | 0.79 | USP2 (0.47) | — | |
| SCHEMBL10499291 | 0.77 | MEN1 (0.43) | MEN1KMT2A | |
| SCHEMBL2717720 | 0.77 | HAVCR2 (0.57) | MEN1KMT2A | |
| SCHEMBL8188099 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0342775-B1 | 4-AMINO-3-ACYLQUINOLINE DERIVATIVES AND THEIR USE AS INHIBITORS OF GASTRIC SECRETION | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1993-09-15 | — | — | EP | disclosed |
| US-5143920-A | Antiulcer, antisecretory | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1992-09-01 | — | — | US | disclosed |
| EP-0342775-A1 | 4-Amino-3-acylquinoline derivatives and their use as inhibitors of gastric secretion | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989008105-A1 | 4-AMINO-3-ACYLQUINOLINE DERIVATIVES AND THEIR USE AS INHIBITORS OF GASTRIC SECRETION | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1989-09-08 | — | — | WO | disclosed |