Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ATP4A | P20648 | 1/20 | 0.47 |
| ▸ | ATP4B | P51164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510106 | 0.86 | MEN1 (0.45) | MEN1KMT2A | |
| SCHEMBL774957 | 0.84 | ATP4A (0.61) | ATP4AATP4B | |
| SCHEMBL9265136 | 0.82 | MEN1 (0.46) | MEN1KMT2A | |
| SCHEMBL9652797 | 0.82 | ATP4A (0.50) | ATP4AATP4B | |
| SCHEMBL9723921 | 0.81 | USP2 (0.47) | ATP4AATP4B | |
| SCHEMBL9506558 | 0.81 | MEN1 (0.45) | MEN1KMT2A | |
| SCHEMBL9267772 | 0.80 | MEN1 (0.44) | MEN1KMT2A | |
| SCHEMBL9723910 | 0.78 | ATP4A (0.78) | ATP4AATP4B | |
| SCHEMBL9652117 | 0.77 | ATP4A (0.54) | ATP4AATP4B | |
| SCHEMBL9265847 | 0.76 | MEN1 (0.47) | MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089498-A | Gastrointestinal disorders | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1992-02-18 | — | — | US | disclosed |
| EP-0339768-A1 | 4-Amino-3-acylquinoline derivatives, and their use as inhibitors of gastric secretion | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1989-11-02 | — | — | EP | disclosed |