Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 10/20 | 0.60 |
| ▸ | RXRA | P19793 | 9/20 | 0.59 |
| ▸ | RXRG | P48443 | 4/20 | 0.59 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | CYP26B1 | Q9NR63 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 5/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8676840 | 0.92 | RXRB (0.71) | RXRBRXRARXRGCYP26A1CYP3A4 | |
| SCHEMBL8674842 | 0.84 | RXRA (0.68) | RXRBRXRARXRGCYP26A1CYP3A4 | |
| SCHEMBL9510301 | 0.83 | PPARG (0.41) | RXRBRXRARXRGCYP26A1CYP3A4 | |
| SCHEMBL6147923 | 0.79 | RXRA (0.67) | RXRBRXRARXRGCYP26A1CYP3A4 | |
| SCHEMBL8776544 | 0.77 | RARB (0.65) | RXRBRXRARXRGCYP26A1CYP3A4 | |
| SCHEMBL8839242 | 0.77 | RXRA (0.69) | RXRBRXRARXRGCYP26A1CYP3A4 | |
| SCHEMBL8134318 | 0.77 | NR4A2 (0.85) | RXRBRXRARXRGNPC1RAB9A | |
| SCHEMBL8674523 | 0.77 | RARA (0.56) | RXRBRXRARXRGCYP26A1CYP3A4 | |
| SCHEMBL8874670 | 0.77 | RXRA (0.64) | RXRBRXRARXRGCYP26A1CYP3A4 | |
| SCHEMBL9275250 | 0.76 | RXRB (0.53) | RXRBRXRARXRGCYP26A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555265-A1 | BICYCLO-COMPOUNDS WITH AN ANTI-SEBORRHOEIC ACTION | Henkel Kommanditgesellschaft auf Aktien (DE) | 1993-08-18 | — | — | EP | disclosed |
| WO-1992006946-A1 | BICYCLO-COMPOUNDS WITH AN ANTI-SEBORRHOEIC ACTION | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1992-04-30 | — | — | WO | disclosed |