Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510386 | 0.90 | SMN1; SMN2 (0.61) | SMN1; SMN2USP2HPGDALDH1A1HSD17B10 | |
| SCHEMBL9510256 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2USP2HPGDALDH1A1HSD17B10 | |
| SCHEMBL9510267 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2USP2HPGDALDH1A1HSD17B10 | |
| SCHEMBL9510328 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2USP2HPGDALDH1A1HSD17B10 | |
| SCHEMBL9510244 | 0.80 | MEN1 (0.53) | SMN1; SMN2ALDH1A1HSD17B10MAPTL3MBTL1 | |
| SCHEMBL9510654 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2USP2HPGDALDH1A1HSD17B10 | |
| SCHEMBL10767715 | 0.80 | TAS1R3 (0.46) | SMN1; SMN2HPGDALDH1A1MAPTLMNA | |
| SCHEMBL31663015 | 0.80 | SMN1; SMN2 (0.58) | SMN1; SMN2USP2HPGDALDH1A1HSD17B10 | |
| SCHEMBL9510307 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2USP2HPGDALDH1A1HSD17B10 | |
| SCHEMBL9510278 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2USP2HPGDALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382216-B1 | Novel substituted acetamide compounds | TOYO BOSEKI (JP) | 1993-10-20 | — | — | EP | claimed |
| US-5041462-A | Novel substituted acetamide compounds and use as anti-allergic agents | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1991-08-20 | — | — | US | claimed |
| EP-0382216-A1 | Novel substituted acetamide compounds | Toyo Boseki Kabushiki Kaisha (JP) | 1990-08-16 | — | — | EP | claimed |
| EP-0382216-B1 | Novel substituted acetamide compounds | TOYO BOSEKI (JP) | 1993-10-20 | — | — | EP | disclosed |
| US-5041462-A | Novel substituted acetamide compounds and use as anti-allergic agents | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1991-08-20 | — | — | US | disclosed |
| EP-0382216-A1 | Novel substituted acetamide compounds | Toyo Boseki Kabushiki Kaisha (JP) | 1990-08-16 | — | — | EP | disclosed |