Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510386 | 0.92 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL9510636 | 0.89 | GAA (0.44) | SMN1; SMN2ALDH1A1GAANLRP3POLB | |
| SCHEMBL9510256 | 0.87 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL9511695 | 0.87 | GAA (0.60) | SMN1; SMN2ALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL9512455 | 0.86 | KDM4E (0.52) | ALDH1A1HSD17B10GAAHPGDNLRP3 | |
| SCHEMBL9510325 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL9510278 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL9510380 | 0.82 | TSHR (0.43) | SMN1; SMN2ALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL9510267 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL9510654 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1HSD17B10GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382216-B1 | Novel substituted acetamide compounds | TOYO BOSEKI (JP) | 1993-10-20 | — | — | EP | claimed |
| US-5041462-A | Novel substituted acetamide compounds and use as anti-allergic agents | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1991-08-20 | — | — | US | claimed |
| EP-0382216-A1 | Novel substituted acetamide compounds | Toyo Boseki Kabushiki Kaisha (JP) | 1990-08-16 | — | — | EP | claimed |
| JP-2209856-A | — | — | None | — | — | JP | disclosed |
| EP-0382216-B1 | Novel substituted acetamide compounds | TOYO BOSEKI (JP) | 1993-10-20 | — | — | EP | disclosed |
| US-5041462-A | Novel substituted acetamide compounds and use as anti-allergic agents | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1991-08-20 | — | — | US | disclosed |
| JP-H02209856-A | NEW SUBSTITUTED ACETAMIDE COMPOUND | TOYOBO CO LTD | 1990-08-21 | — | — | JP | disclosed |
| EP-0382216-A1 | Novel substituted acetamide compounds | Toyo Boseki Kabushiki Kaisha (JP) | 1990-08-16 | — | — | EP | disclosed |