Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511695 | 0.88 | GAA (0.60) | KDM4EHSD17B10KMT2AGAAALDH1A1 | |
| SCHEMBL9512510 | 0.88 | KDM4E (0.53) | KDM4EPOLBHSD17B10KMT2AGAA | |
| SCHEMBL9510328 | 0.86 | SMN1; SMN2 (0.53) | POLBHSD17B10GAAALDH1A1HPGD | |
| SCHEMBL9510636 | 0.85 | GAA (0.44) | POLBKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL9510380 | 0.83 | TSHR (0.43) | KDM4EHSD17B10KMT2AGAAMEN1 | |
| SCHEMBL11631534 | 0.79 | GAA (0.64) | KDM4EKMT2AGAAALDH1A1HPGD | |
| SCHEMBL11737164 | 0.78 | GPR35 (0.46) | GAAALDH1A1CYP1A2TSHRCYP2C19 | |
| SCHEMBL9510386 | 0.76 | SMN1; SMN2 (0.61) | POLBHSD17B10GAAALDH1A1HPGD | |
| SCHEMBL9510315 | 0.74 | GAA (0.63) | KDM4EPOLBHSD17B10KMT2AGAA | |
| SCHEMBL9510256 | 0.72 | SMN1; SMN2 (0.56) | KDM4EPOLBHSD17B10GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382216-B1 | Novel substituted acetamide compounds | TOYO BOSEKI (JP) | 1993-10-20 | — | — | EP | claimed |
| US-5041462-A | Novel substituted acetamide compounds and use as anti-allergic agents | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1991-08-20 | — | — | US | claimed |
| EP-0382216-A1 | Novel substituted acetamide compounds | Toyo Boseki Kabushiki Kaisha (JP) | 1990-08-16 | — | — | EP | claimed |
| EP-0382216-B1 | Novel substituted acetamide compounds | TOYO BOSEKI (JP) | 1993-10-20 | — | — | EP | disclosed |
| US-5041462-A | Novel substituted acetamide compounds and use as anti-allergic agents | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1991-08-20 | — | — | US | disclosed |
| EP-0382216-A1 | Novel substituted acetamide compounds | Toyo Boseki Kabushiki Kaisha (JP) | 1990-08-16 | — | — | EP | disclosed |