SCHEMBL9510339

SCHEMBL9510339

CC1=NN(c2cc(C(=O)O)cc(C(=O)O)c2)CC1=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 2/20 0.45
TPMT P51580 1/20 0.41
NSD2 O96028 1/20 0.39
G6PD P11413 1/20 0.39
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
POLB P06746 3/20 0.38
KDM4E B2RXH2 3/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
HTT P42858 2/20 0.38
CASP6 P55212 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.38
HCAR1 Q9BXC0 1/20 0.37
KMT2A Q03164 5/20 0.36
MAPT P10636 4/20 0.36
ALDH1A1 P00352 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MEN1 O00255 3/20 0.35
GAA P10253 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9805803 0.85 KMT2A (0.51) NR4A1NSD2POLBKDM4EL3MBTL1
SCHEMBL8629565 0.84 POLB (0.50) POLBKDM4EHTTKMT2AMAPT
SCHEMBL5425655 0.73 MAPT (0.43) POLBKDM4EL3MBTL1HTTKMT2A
SCHEMBL11293395 0.68 MAPT (0.50) POLBKDM4EL3MBTL1HTTKMT2A
SCHEMBL9854205 0.68 MAPT (0.58) NR4A1POLBKDM4EL3MBTL1HTT
SCHEMBL9309242 0.67 KAT8 (0.41) KDM4EL3MBTL1HTTCASP6KMT2A
SCHEMBL9512623 0.66 POLB (0.44) POLBKDM4EL3MBTL1HTTKMT2A
SCHEMBL40661 0.65 TPMT (0.89) NR4A1TPMTKDM4EHCAR1MAPT
SCHEMBL11443323 0.65 NSD2 (0.55) NR4A1TPMTNSD2G6PDKEAP1
Cyclopropane SCHEMBL28772593 0.64 TPMT (0.76) NR4A1TPMTKDM4EHCAR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0323729-B1 SOLID PARTICLE DISPERSIONS OF DYES USEFUL IN PHOTOGRAPHIC ELEMENTS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1993-09-29 EP disclosed
EP-0294461-B1 SOLID PARTICLE DISPERSION FILTER DYES FOR PHOTOGRAPHIC COMPOSITIONS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1991-10-23 EP disclosed
US-4948718-A FILTER DYES EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed
US-4900652-A FILM SUPPORT CAPABLE OF TRANSMITTING RADIATION. EASTMAN KODAK COMPANY (US) 1990-02-13 US disclosed
EP-0323729-A2 Solid particle dispersions of dyes useful in photographic elements EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-07-12 EP disclosed
EP-0294461-A1 SOLID PARTICLE DISPERSION FILTER DYES FOR PHOTOGRAPHIC COMPOSITIONS. EASTMAN KODAK CO (US) 1988-12-14 EP disclosed
WO-1988004794-A1 SOLID PARTICLE DISPERSION FILTER DYES FOR PHOTOGRAPHIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1988-06-30 WO disclosed