Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 1/20 | 0.62 |
| ▸ | ATP4B | P51164 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847409 | 0.89 | ATP4A (0.78) | ATP4AATP4B | |
| SCHEMBL9506605 | 0.88 | ATP4A (0.80) | ATP4AATP4B | |
| Hydrochloric Acid SCHEMBL11233459 | 0.88 | ATP4A (0.76) | ATP4AATP4B | |
| SCHEMBL11245876 | 0.87 | ATP4A (0.68) | ATP4AATP4BMEN1ALDH1A1LMNA | |
| SCHEMBL11243344 | 0.86 | MAPT (0.80) | MEN1ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL23493688 | 0.86 | MAPT (0.72) | MEN1ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL11237205 | 0.86 | ATP4A (0.67) | ATP4AATP4B | |
| SCHEMBL31307860 | 0.86 | MAPT (0.72) | MEN1ALDH1A1LMNAMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL11235097 | 0.86 | ATP4A (0.67) | ATP4AATP4BMEN1ALDH1A1LMNA | |
| SCHEMBL11230008 | 0.86 | MEN1 (0.66) | ATP4AATP4BMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0342775-B1 | 4-AMINO-3-ACYLQUINOLINE DERIVATIVES AND THEIR USE AS INHIBITORS OF GASTRIC SECRETION | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1993-09-15 | — | — | EP | disclosed |
| US-5143920-A | Antiulcer, antisecretory | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1992-09-01 | — | — | US | disclosed |
| EP-0342775-A1 | 4-Amino-3-acylquinoline derivatives and their use as inhibitors of gastric secretion | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1989-11-23 | — | — | EP | disclosed |