Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ATF4 | P18848 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442550 | 0.77 | MMP2 (0.46) | NPSR1KMT2AL3MBTL1MMP2MMP8 | |
| SCHEMBL6762220 | 0.72 | EPHX2 (0.43) | NPSR1L3MBTL1MMP2MMP8LMNA | |
| SCHEMBL7573633 | 0.71 | MMP2 (0.52) | KMT2AMMP2MMP8CA12CA1 | |
| SCHEMBL14671386 | 0.71 | MMP2 (0.41) | NPSR1KMT2AL3MBTL1MMP2MMP8 | |
| SCHEMBL13681670 | 0.71 | NPSR1 (0.52) | NPSR1KMT2AL3MBTL1LMNAATF4 | |
| SCHEMBL12446601 | 0.70 | MMP2 (0.57) | NPSR1KMT2AMMP2MMP8CA12 | |
| SCHEMBL2717779 | 0.70 | POLB (0.40) | KMT2AMMP2MMP8CA12CA1 | |
| SCHEMBL8866823 | 0.69 | CTSA (0.39) | L3MBTL1TSHR | |
| SCHEMBL8002995 | 0.69 | TDP1 (0.40) | KMT2AL3MBTL1LMNAHPGDTSHR | |
| SCHEMBL18199497 | 0.67 | RAB9A (0.49) | NPSR1KMT2AL3MBTL1LMNASMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569409-A1 | AMIDE DERIVATIVES AND THEIR THERAPEUTIC USE | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-11-18 | — | — | EP | disclosed |
| WO-1992012959-A1 | AMIDE DERIVATIVES AND THEIR THERAPEUTIC USE | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-08-06 | — | — | WO | disclosed |