Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | AGER | Q15109 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1060005 | 0.81 | KDM4E (1.00) | KDM4EMAPTCYP1A2ALDH1A1ALOX15 | |
| SCHEMBL29766826 | 0.81 | KDM4E (1.00) | KDM4EMAPTCYP1A2ALDH1A1ALOX15 | |
| SCHEMBL30583181 | 0.80 | KDM4E (0.62) | KDM4EMAPTCYP1A2ALDH1A1ALOX15 | |
| SCHEMBL1983224 | 0.80 | KDM4E (0.62) | KDM4EMAPTCYP1A2ALDH1A1ALOX15 | |
| SCHEMBL27231741 | 0.77 | KDM4E (0.72) | KDM4EMAPTCYP1A2ALDH1A1ALOX15 | |
| SCHEMBL990359 | 0.75 | KDM4E (0.70) | KDM4EMAPTCYP1A2ALDH1A1ALOX15 | |
| Benzene SCHEMBL11818131 | 0.75 | KDM4E (0.70) | KDM4EMAPTCYP1A2ALDH1A1ALOX15 | |
| SCHEMBL353589 | 0.75 | KDM4E (0.70) | KDM4EMAPTCYP1A2ALDH1A1ALOX15 | |
| SCHEMBL9603138 | 0.75 | KDM4E (0.55) | KDM4EMAPTCYP1A2ALDH1A1ALOX15 | |
| SCHEMBL131588 | 0.74 | KDM4E (0.68) | KDM4EMAPTCYP1A2ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557375-A1 | NEW HETEROCYCLIC COMPOUNDS AS ANTAGONISTS OF EXCITATORY AMINO ACID RECEPTORS, PROCESSES FOR THEIR PREPARATION AND THEIR USE | Astra Aktiebolag (SE) | 1993-09-01 | — | — | EP | disclosed |
| WO-1992008724-A1 | NEW HETEROCYCLIC COMPOUNDS AS ANTAGONISTS OF EXCITATORY AMINO ACID RECEPTORS, PROCESSES FOR THEIR PREPARATION AND THEIR USE | AKTIEBOLAGET ASTRA (SE) | 1992-05-29 | — | — | WO | disclosed |