Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | AGER | Q15109 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27231741 | 0.86 | KDM4E (0.72) | KDM4EMAPTCYP1A2L3MBTL1ALDH1A1 | |
| SCHEMBL14358101 | 0.85 | KDM4E (0.66) | KDM4EMAPTCYP1A2L3MBTL1ALDH1A1 | |
| SCHEMBL353589 | 0.84 | KDM4E (0.70) | KDM4EMAPTCYP1A2L3MBTL1ALDH1A1 | |
| Benzene SCHEMBL11818131 | 0.84 | KDM4E (0.70) | KDM4EMAPTCYP1A2L3MBTL1ALDH1A1 | |
| SCHEMBL1060005 | 0.82 | KDM4E (1.00) | KDM4EMAPTCYP1A2L3MBTL1ALDH1A1 | |
| SCHEMBL13118201 | 0.82 | KDM4E (0.49) | KDM4EMAPTCYP1A2L3MBTL1ALDH1A1 | |
| SCHEMBL131588 | 0.82 | KDM4E (0.68) | KDM4EMAPTCYP1A2L3MBTL1ALDH1A1 | |
| SCHEMBL8710514 | 0.82 | KDM4E (0.68) | KDM4EMAPTCYP1A2L3MBTL1ALDH1A1 | |
| SCHEMBL2149140 | 0.82 | KDM4E (0.68) | KDM4EMAPTCYP1A2L3MBTL1ALDH1A1 | |
| SCHEMBL29766826 | 0.82 | KDM4E (1.00) | KDM4EMAPTCYP1A2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110157251-B | Curing agent composition and coating composition comprising same | ＫＣＣ公司 | 2022-04-01 | — | — | CN | claimed |
| EP-2448913-B1 | CONTINUOUS METHOD FOR ACYLATING AMINO GROUP-CARRYING ORGANIC ACIDS | CLARIANT FINANCE BVI LTD (VG) | 2013-04-24 | — | — | EP | claimed |
| EP-2448904-B1 | CONTINUOUS METHOD FOR PRODUCING ESTERS OF AROMATIC CARBOXYLIC ACIDS | CLARIANT FINANCE BVI LTD (VG) | 2013-04-17 | — | — | EP | claimed |
| EP-2448904-A2 | CONTINUOUS METHOD FOR PRODUCING ESTERS OF AROMATIC CARBOXYLIC ACIDS | Clariant Finance (BVI) Limited (VG) | 2012-05-09 | — | — | EP | claimed |
| EP-2448913-A2 | CONTINUOUS METHOD FOR ACYLATING AMINO GROUP-CARRYING ORGANIC ACIDS | Clariant Finance (BVI) Limited (VG) | 2012-05-09 | — | — | EP | claimed |
| US-20120090983-A1 | Continuous Method For Acylating Amino Group-Carrying Organic Acids | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-04-19 | — | — | US | claimed |
| US-20120088918-A1 | Continuous Method For Producing Esters Of Aromatic Carboxylic Acids | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-04-12 | — | — | US | claimed |
| EP-2300433-A1 | HIV INTEGRASE INHIBITORS FROM PYRIDOXINE | Ambrilia Biopharma Inc. (CA) | 2011-03-30 | — | — | EP | claimed |
| WO-2011000464-A2 | CONTINUOUS METHOD FOR PRODUCING ESTERS OF AROMATIC CARBOXYLIC ACIDS | CLARIANT INTERNATIONAL LTD (CH) | 2011-01-06 | — | — | WO | claimed |
| WO-2011000461-A2 | CONTINUOUS METHOD FOR ACYLATING AMINO GROUP-CARRYING ORGANIC ACIDS | CLARIANT INTERNATIONAL LTD (CH) | 2011-01-06 | — | — | WO | claimed |
| WO-2009146555-A1 | HIV INTEGRASE INHIBITORS FROM PYRIDOXINE | AMBRILIA BIOPHARMA INC. (CA) | 2009-12-10 | — | — | WO | claimed |
| US-11931348-B2 | Methods of treating elevated plasma cholesterol | Montréal Heart Institute (CA) | 2024-03-19 | — | — | US | disclosed |
| US-20230088095-A1 | METHODS OF TREATING ELEVATED PLASMA CHOLESTEROL | Montréal Heart Institute (CA) | 2023-03-23 | — | — | US | disclosed |
| CN-114641554-A | Method for improving electrochemiluminescence signal in bioanalytical assays | 苏州安赛诊断技术有限公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-108698047-B | Branched amines in electrochemiluminescence detection | 豪夫迈·罗氏有限公司 | 2022-04-01 | — | — | CN | disclosed |
| EP-2200967-A2 | NEW NO-DONOR ASPIRIN DERIVATIVES | Nicox S.A. (FR) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009146555-A1 | HIV INTEGRASE INHIBITORS FROM PYRIDOXINE | AMBRILIA BIOPHARMA INC. (CA) | 2009-12-10 | — | — | WO | disclosed |
| WO-2009121484-A1 | CONTINUOUS METHOD FOR PRODUCING AMIDES OF AROMATIC CARBOXYLIC ACIDS | CLARIANT INTERNATIONAL LTD (CH) | 2009-10-08 | — | — | WO | disclosed |
| WO-2009121488-A1 | METHOD FOR PRODUCING AMIDES IN THE PRESENCE OF SUPERHEATED WATER | CLARIANT INTERNATIONAL LTD (CH) | 2009-10-08 | — | — | WO | disclosed |
| WO-2009049961-A2 | NEW NO-DONOR ASPIRIN DERIVATIVES | NICOX S.A. (FR) | 2009-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11931348-B2 | Methods of treating elevated plasma cholesterol | CETP, LDLR, APOB | KDM4E 4383/4885MAPT 2023/4885CYP1A2 304/4885 |
| US-20230088095-A1 | METHODS OF TREATING ELEVATED PLASMA CHOLESTEROL | CETP, LDLR, APOB | KDM4E 4383/4885MAPT 2023/4885CYP1A2 304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.