Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | AR | P10275 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TXN | P10599 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512670 | 0.85 | ALDH1A1 (0.83) | BCHERAB9ANPC1ALDH1A1EPHX2 | |
| SCHEMBL10766969 | 0.85 | ALDH1A1 (0.74) | BCHERAB9ANPC1ALDH1A1EPHX2 | |
| SCHEMBL8098342 | 0.83 | RAB9A (0.82) | BCHERAB9ANPC1ALDH1A1EPHX2 | |
| SCHEMBL11475158 | 0.82 | BCHE (1.00) | BCHERAB9ANPC1ALDH1A1EPHX2 | |
| SCHEMBL9012473 | 0.82 | KMT2A (0.63) | BCHERAB9ANPC1ALDH1A1EPHX2 | |
| SCHEMBL2236478 | 0.81 | TSHR (0.63) | ALDH1A1SMN1; SMN2POLBLMNAHPGD | |
| Hydrochloric Acid SCHEMBL10492814 | 0.80 | TSHR (0.48) | BCHERAB9ANPC1ALDH1A1EPHX2 | |
| Hydrochloric Acid SCHEMBL10492839 | 0.80 | TSHR (0.48) | BCHERAB9ANPC1ALDH1A1AR | |
| SCHEMBL425175 | 0.80 | RAB9A (1.00) | BCHERAB9ANPC1ALDH1A1EPHX2 | |
| SCHEMBL10871003 | 0.80 | ALDH1A1 (0.67) | BCHERAB9ANPC1ALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214796-B2 | Process for production of 1-[2-(benzimidazol-2-yl-thio)ethyl]piperazine or salts thereof | KOWA CO., LTD. (JP) | 2007-05-08 | — | — | US | disclosed |
| EP-0334818-B1 | Pharmacologically active alkylthiobenz imidazole derivatives and process for the preparation thereof | DOMPE FARMACEUTICI SPA (IT) | 1993-12-01 | — | — | EP | disclosed |
| US-4983620-A | ANTIHISTAMINES, ANTIALLERGENS | DOMPE FARMACEUTICI S.P.A. (IT) | 1991-01-08 | — | — | US | disclosed |
| EP-0334818-A1 | Pharmacologically active alkylthiobenz imidazole derivatives and process for the preparation thereof | DOMPE' FARMACEUTICI S.p.A. (IT) | 1989-09-27 | — | — | EP | disclosed |