SCHEMBL9511142

SCHEMBL9511142

O=C(Cl)c1ccc2c(c1)Sc1ccc(C(=O)Cl)cc1S2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
TSHR P16473 4/20 0.37
MAPT P10636 3/20 0.36
NOX1 Q9Y5S8 3/20 0.36
ALOX15 P16050 2/20 0.36
MEN1 O00255 1/20 0.36
CYBB P04839 1/20 0.36
APP P05067 1/20 0.36
GAA P10253 1/20 0.36
SNCA P37840 1/20 0.36
KMT2A Q03164 1/20 0.36
NOX3 Q9HBY0 1/20 0.36
NOX4 Q9NPH5 1/20 0.36
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
BCHE P06276 3/20 0.33
ACHE P22303 2/20 0.33
CES2 O00748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29007331 1.00 ALDH1A1 (0.38) ALDH1A1TSHRMAPTNOX1ALOX15
SCHEMBL11042557 0.94 MAPT (0.44) ALDH1A1TSHRMAPTNOX1ALOX15
SCHEMBL30875825 0.82 ALOX5 (0.35) ALDH1A1TSHRMAPTNOX1ALOX15
SCHEMBL28490226 0.79 NOX1 (0.46) MAPTNOX1ALOX15MEN1CYBB
SCHEMBL28476906 0.79 MAPT (0.58) MAPTNOX1ALOX15MEN1CYBB
SCHEMBL68522 0.79 TSHR (0.50) ALDH1A1TSHRMAPTALOX15GAA
SCHEMBL12106079 0.79 TSHR (0.50) ALDH1A1TSHRMAPTALOX15GAA
SCHEMBL28481967 0.78 NOX1 (0.56) MAPTNOX1ALOX15MEN1CYBB
SCHEMBL9511394 0.77 MAPT (0.36) ALDH1A1MAPTNOX1ALOX15MEN1
SCHEMBL9511380 0.77 MAPT (0.56) ALDH1A1TSHRMAPTNOX1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115850699-B Low-dielectric blended polyimide and preparation method and application thereof 江西有泽新材料科技有限公司 2024-04-26 CN disclosed
CN-115850699-A Low-dielectric blended polyimide, preparation method and application thereof 江西有泽新材料科技有限公司 2023-03-28 CN disclosed
EP-0399293-B1 PROCESS FOR PREPARING 2-CHLORO-4-NITRO-ALKYLBENZENE BAYER AG (DE) 1993-09-01 EP disclosed
US-5095157-A Friedel-crafts catalyst BAYER AKTIENGESELLSCHAFT (DE) 1992-03-10 US disclosed
EP-0399293-A1 Process for preparing 2-chloro-4-nitro-alkylbenzene BAYER AG (DE) 1990-11-28 EP disclosed