Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.53 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5130815 | 0.84 | HSD17B10 (0.67) | SMN1; SMN2CASP3SENP7SENP6ALDH1A1 | |
| SCHEMBL9508846 | 0.81 | NPC1 (0.51) | SMN1; SMN2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL5127850 | 0.80 | ITGB1 (0.44) | SMN1; SMN2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL460247 | 0.79 | TTR (0.69) | CASP3SENP7SENP6TTRALB | |
| SCHEMBL10590415 | 0.78 | PIK3CG (0.54) | PIK3CGPSMB8PSMB5SMN1; SMN2CASP3 | |
| SCHEMBL9511231 | 0.78 | PIK3CG (0.54) | PIK3CGPSMB8PSMB5SMN1; SMN2CASP3 | |
| SCHEMBL2242624 | 0.78 | SMN1; SMN2 (0.76) | PIK3CGPSMB8PSMB5SMN1; SMN2CASP3 | |
| SCHEMBL10590678 | 0.77 | SMN1; SMN2 (0.61) | PIK3CGPSMB8PSMB5SMN1; SMN2CASP3 | |
| SCHEMBL1250272 | 0.76 | MAPT (0.63) | SMN1; SMN2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL23748387 | 0.75 | SMN1; SMN2 (0.71) | PIK3CGSMN1; SMN2CASP3SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345513-B1 | POLYARYLENEETHERS HAVING BENZOXAZOLE GROUPS AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1993-09-08 | — | — | EP | disclosed |
| US-4960855-A | Polyarylene ether containing benzoxazole groups and a process for their preparation | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |
| EP-0345513-A1 | Polyaryleneethers having benzoxazole groups and process for their preparation | BAYER AG (DE) | 1989-12-13 | — | — | EP | disclosed |