Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 2/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 8/20 | 0.48 |
| ▸ | RAB9A | P51151 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10385204 | 0.92 | MAPT (0.53) | PIK3CGESR1ESR2APEX1PSMB8 | |
| SCHEMBL9196865 | 0.89 | ESR1 (0.68) | ESR1ESR2APEX1 | |
| SCHEMBL7573646 | 0.87 | NPC1 (0.56) | ESR1ESR2NPC1RAB9AALDH1A1 | |
| SCHEMBL10590415 | 0.86 | PIK3CG (0.54) | PIK3CGESR1ESR2PSMB8PSMB5 | |
| SCHEMBL12704759 | 0.84 | TTR (0.66) | ESR1ESR2APEX1NPC1RAB9A | |
| SCHEMBL2245145 | 0.84 | NPC1 (0.57) | ESR1ESR2APEX1NPC1RAB9A | |
| SCHEMBL4514393 | 0.81 | MAPT (0.60) | PIK3CGPSMB8PSMB5NPC1RAB9A | |
| SCHEMBL14409198 | 0.80 | ESR1 (0.77) | ESR1ESR2 | |
| SCHEMBL11744415 | 0.80 | MAPT (0.61) | PIK3CGESR1ESR2NPC1RAB9A | |
| SCHEMBL2492941 | 0.80 | MAPT (0.72) | ESR1ESR2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345513-B1 | POLYARYLENEETHERS HAVING BENZOXAZOLE GROUPS AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1993-09-08 | — | — | EP | disclosed |
| US-4960855-A | Polyarylene ether containing benzoxazole groups and a process for their preparation | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |
| EP-0345513-A1 | Polyaryleneethers having benzoxazole groups and process for their preparation | BAYER AG (DE) | 1989-12-13 | — | — | EP | disclosed |
| EP-0332997-A2 | Poly(arylene sulphides) containing benzoxazol or oxazoline groups | BAYER AG (DE) | 1989-09-20 | — | — | EP | disclosed |