Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP8 | P40818 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510064 | 0.82 | TRPV4 (0.43) | MAOAMAOBALDH1A1TRPV4CYP2A6 | |
| SCHEMBL9511348 | 0.80 | MEN1 (0.31) | — | |
| SCHEMBL56906 | 0.75 | USP8 (0.40) | USP8USP7MAOAMAOBKDM4E | |
| SCHEMBL9508100 | 0.73 | SMN1; SMN2 (0.41) | KDM4EUSP2ALDH1A1TSHR | |
| SCHEMBL9511220 | 0.71 | MAOB (0.35) | MAOAMAOB | |
| SCHEMBL30718953 | 0.69 | CA1 (0.42) | USP8USP7MAOAMAOBKDM4E | |
| SCHEMBL1271039 | 0.69 | CA1 (0.42) | USP8USP7MAOAMAOBKDM4E | |
| SCHEMBL8815916 | 0.69 | USP8 (0.37) | USP8USP7MAOAMAOBKDM4E | |
| SCHEMBL9511376 | 0.69 | AHR (0.39) | ALDH1A1TRPV4 | |
| SCHEMBL9511458 | 0.67 | SNCA (0.47) | ALDH1A1TSHRCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399293-B1 | PROCESS FOR PREPARING 2-CHLORO-4-NITRO-ALKYLBENZENE | BAYER AG (DE) | 1993-09-01 | — | — | EP | disclosed |
| US-5095157-A | Friedel-crafts catalyst | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-10 | — | — | US | disclosed |
| EP-0399293-A1 | Process for preparing 2-chloro-4-nitro-alkylbenzene | BAYER AG (DE) | 1990-11-28 | — | — | EP | disclosed |