Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511227 | 0.73 | USP8 (0.33) | KDM4EALDH1A1TSHRUSP2 | |
| SCHEMBL9511243 | 0.69 | SMN1; SMN2 (0.35) | SMN1; SMN2KDM4EL3MBTL1ALDH1A1GAA | |
| SCHEMBL8757233 | 0.69 | SMN1; SMN2 (0.41) | SMN1; SMN2KDM4EL3MBTL1ALDH1A1GAA | |
| SCHEMBL8670727 | 0.69 | KDM4E (0.45) | SMN1; SMN2KDM4EL3MBTL1ALDH1A1GAA | |
| SCHEMBL12082332 | 0.68 | HTT (0.51) | SMN1; SMN2KDM4EALDH1A1GAAMEN1 | |
| SCHEMBL16051600 | 0.68 | CYP1A2 (0.49) | SMN1; SMN2KDM4EL3MBTL1POLBHPGD | |
| SCHEMBL14620529 | 0.68 | KDM4E (0.49) | SMN1; SMN2KDM4EL3MBTL1ALDH1A1GAA | |
| SCHEMBL14739172 | 0.68 | KDM4E (0.49) | SMN1; SMN2KDM4EL3MBTL1ALDH1A1GAA | |
| SCHEMBL2532385 | 0.68 | GABRA1 (0.46) | SMN1; SMN2KDM4EL3MBTL1GAATSHR | |
| SCHEMBL8671847 | 0.66 | ALDH1A1 (0.59) | SMN1; SMN2KDM4EALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399293-B1 | PROCESS FOR PREPARING 2-CHLORO-4-NITRO-ALKYLBENZENE | BAYER AG (DE) | 1993-09-01 | — | — | EP | disclosed |
| US-5095157-A | Friedel-crafts catalyst | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-10 | — | — | US | disclosed |
| EP-0399293-A1 | Process for preparing 2-chloro-4-nitro-alkylbenzene | BAYER AG (DE) | 1990-11-28 | — | — | EP | disclosed |