Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.56 |
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | CASP3 | P42574 | 2/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.54 |
| ▸ | HPGD | P15428 | 7/20 | 0.53 |
| ▸ | TP53 | P04637 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10385204 | 0.95 | MAPT (0.53) | NPC1RAB9AALDH1A1KDM4ECASP3 | |
| SCHEMBL2133422 | 0.87 | AGPAT2 (0.61) | NPC1RAB9AALDH1A1KDM4ECASP3 | |
| SCHEMBL9511231 | 0.87 | PIK3CG (0.54) | NPC1RAB9AALDH1A1KDM4ECASP3 | |
| SCHEMBL12861182 | 0.86 | PTGS2 (0.60) | NPC1RAB9AALDH1A1KDM4ECASP3 | |
| SCHEMBL7578683 | 0.84 | ESR1 (0.52) | NPC1RAB9AALDH1A1KDM4ECASP3 | |
| SCHEMBL11869096 | 0.84 | KDM4E (0.55) | NPC1RAB9AALDH1A1KDM4ECASP3 | |
| SCHEMBL5307394 | 0.84 | MAPT (0.59) | NPC1RAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL24155398 | 0.83 | SMN1; SMN2 (0.61) | NPC1RAB9AALDH1A1KDM4ECASP3 | |
| SCHEMBL16459759 | 0.83 | NPC1 (0.67) | NPC1RAB9AALDH1A1KDM4ECASP3 | |
| SCHEMBL13522796 | 0.81 | KDM6B (0.73) | NPC1RAB9AALDH1A1KDM4ECASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105061348-B | A kind of preparation method of 2 substituted benzene Bing oxazole compounds | 河南师范大学 | 2017-12-12 | — | — | CN | disclosed |
| CN-105061348-A | Method for preparing 2-substituted benzoxazole compound | UNIV HENAN NORMAL | 2015-11-18 | — | — | CN | disclosed |
| US-8206838-B2 | Matrix comprises aromatic repeat units and luminescent metal ion/complex; photoluminescent; phosphors | SUMITOMO CHEMICAL CO., LTD. (JP) | 2012-06-26 | — | — | US | disclosed |
| US-8206838-B2 | Matrix comprises aromatic repeat units and luminescent metal ion/complex; photoluminescent; phosphors | SUMITOMO CHEMICAL CO., LTD. (JP) | 2012-06-26 | — | — | US | disclosed |
| EP-0773248-B1 | Polymers with heterocyclic side groups | MISSISSIPPI POLYMER TECHNOLOGI (US) | 2002-10-02 | — | — | EP | disclosed |
| US-5668245-A | PHENYLENE POLYMERS WITH HETEROCYCLIC SIDE GROUPS | MAXDEM INCORPORATED (US) | 1997-09-16 | — | — | US | disclosed |
| EP-0773248-A1 | Polymers with heterocyclic side groups | MAXDEM INCORPORATED (US) | 1997-05-14 | — | — | EP | disclosed |
| EP-0623115-A4 | NUCLEOPHILIC DISPLACEMENT METHOD FOR SYNTHESIS OF NON-RIGID PBZ POLYMERS. | DOW CHEMICAL CO (US) | 1995-01-11 | — | — | EP | disclosed |
| EP-0623115-A1 | NUCLEOPHILIC DISPLACEMENT METHOD FOR SYNTHESIS OF NON-RIGID PBZ POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1994-11-09 | — | — | EP | disclosed |
| EP-0345513-B1 | POLYARYLENEETHERS HAVING BENZOXAZOLE GROUPS AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1993-09-08 | — | — | EP | disclosed |
| WO-1993014071-A1 | NUCLEOPHILIC DISPLACEMENT METHOD FOR SYNTHESIS OF NON-RIGID PBZ POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1993-07-22 | — | — | WO | disclosed |
| US-5216110-A | Monomers useful in nucleophilic displacement synthesis of polybenzazole polymers | THE DOW CHEMICAL COMPANY (US) | 1993-06-01 | — | — | US | disclosed |
| US-5194562-A | Nucleophilic displacement method for synthesis of non-rigid PBZ polymers | THE DOW CHEMICAL COMPANY (US) | 1993-03-16 | — | — | US | disclosed |
| US-5104960-A | Nucleophilic displacement method for synthesis of non-rigid PBZ polymers | THE DOW CHEMICAL COMPANY (US) | 1992-04-14 | — | — | US | disclosed |
| US-4960855-A | Polyarylene ether containing benzoxazole groups and a process for their preparation | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |
| EP-0345513-A1 | Polyaryleneethers having benzoxazole groups and process for their preparation | BAYER AG (DE) | 1989-12-13 | — | — | EP | disclosed |
| EP-0332997-A2 | Poly(arylene sulphides) containing benzoxazol or oxazoline groups | BAYER AG (DE) | 1989-09-20 | — | — | EP | disclosed |