Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.40 |
| ▸ | FABP7 | O15540 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30983194 | 0.82 | CASP3 (0.50) | CASP3KMT2AFABP5FABP7CYP1A2 | |
| SCHEMBL9188706 | 0.82 | CASP3 (0.50) | CASP3KMT2AFABP5FABP7CYP1A2 | |
| SCHEMBL7123965 | 0.82 | CASP3 (0.50) | CASP3KMT2AFABP5FABP7CYP1A2 | |
| SCHEMBL4263538 | 0.81 | KMT2A (0.51) | CASP3KMT2AFABP5FABP7EPHX2 | |
| SCHEMBL28458423 | 0.81 | KMT2A (0.44) | CASP3KMT2AFABP5FABP7EPHX2 | |
| SCHEMBL31047777 | 0.81 | KMT2A (0.44) | CASP3KMT2AFABP5FABP7EPHX2 | |
| SCHEMBL4690511 | 0.79 | KMT2A (0.47) | CASP3KMT2AFABP5FABP7CYP1A2 | |
| SCHEMBL30935801 | 0.79 | FABP5 (0.43) | CASP3KMT2AFABP5FABP7EPHX2 | |
| SCHEMBL1096890 | 0.77 | CASP3 (0.44) | CASP3KMT2AEPHX2MDM4TP53 | |
| SCHEMBL31540857 | 0.77 | KMT2A (0.50) | CASP3KMT2AFABP5FABP7CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0401177-B1 | SYNTHETIC PEPTIDE ANTAGONISTS OF NEUROKININ A, SALTS THEREOF AND RESPECTIVE PREPARATION PROCESSES | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1993-09-08 | — | — | EP | disclosed |
| US-5128447-A | Bronchodilation, antispasmodic for intestines or bladder | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1992-07-07 | — | — | US | disclosed |
| EP-0401177-A1 | Synthetic peptide antagonists of neurokinin A, salts thereof and respective preparation processes | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1990-12-05 | — | — | EP | disclosed |