Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | TPMT | P51580 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | TTR | P02766 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8406653 | 0.82 | RXRA (0.61) | ALDH1A1MRGPRX4MAPTCYP2C9 | |
| SCHEMBL23479774 | 0.82 | LMNA (0.61) | LMNACA12CA1CA2CA4 | |
| SCHEMBL8797195 | 0.80 | TTR (0.49) | LMNACA12CA1CA2CA4 | |
| SCHEMBL11598781 | 0.80 | TSHR (0.49) | LMNATSHRTTRRAB9AALDH1A1 | |
| SCHEMBL402416 | 0.80 | CA12 (0.62) | LMNACA12CA1CA2CA4 | |
| SCHEMBL406852 | 0.79 | TTR (0.45) | LMNATSHRTTRRAB9APTGDR2 | |
| SCHEMBL7368821 | 0.79 | CA12 (0.67) | LMNACA12CA1CA2CA4 | |
| SCHEMBL9285065 | 0.78 | HDAC4 (0.59) | LMNACA12CA1CA2CA7 | |
| SCHEMBL8889851 | 0.78 | LMNA (0.54) | LMNACA12CA1CA2CA4 | |
| SCHEMBL410382 | 0.78 | TSHR (0.56) | LMNATSHRTTRTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379290-B1 | Flux composition | COOKSON GROUP PLC (GB) | 1993-10-27 | — | — | EP | claimed |